eF-site ID 2w5e-E PDB Code 2w5e Chain E click to enlarge Title Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution Classification HYDROLASE Compound PUTATIVE SERINE PROTEASE Source Human astrovirus-1 (HAstV-1) (Q3ZN04_HASV1) Sequence E:  KHHHHHHIKPGALCVIDTPEGKGTGFFSGNDIVTAAHVVG NNTFVNVCYEGLMYEAKVRYMPEKDIAFITCPGDLHPTAR LKLSKNPDYSCVTVMAYVNEDLVVSTAAAMVYGNTLSYAV RTQDGMSGAPVCDKYCRVLAVHQTNTGYTGGAVIIDPTDF HP Description (1)  PUTATIVE SERINE PROTEASE Functional site 1) chain E residue 500 type sequence H description BINDING SITE FOR RESIDUE CD C 1587 source : BC6 2) chain E residue -2 type sequence H description BINDING SITE FOR RESIDUE CD E 1587 source : DC4 3) chain E residue -4 type sequence H description BINDING SITE FOR RESIDUE CD E 1587 source : DC4 4) chain E residue -3 type sequence H description BINDING SITE FOR RESIDUE CL E 1588 source : DC5 5) chain E residue -4 type sequence H description BINDING SITE FOR RESIDUE CL E 1588 source : DC5 6) chain E residue 514 type sequence S description BINDING SITE FOR RESIDUE CL E 1589 source : DC6 7) chain E residue 515 type sequence C description BINDING SITE FOR RESIDUE CL E 1589 source : DC6 8) chain E residue -3 type sequence H description BINDING SITE FOR RESIDUE CD E 1590 source : DC7 9) chain E residue -5 type sequence H description BINDING SITE FOR RESIDUE CD E 1590 source : DC7 10) chain E residue 515 type sequence C description BINDING SITE FOR RESIDUE CD E 1590 source : DC7 11) chain E residue -6 type sequence H description BINDING SITE FOR RESIDUE CL E 1591 source : DC8 12) chain E residue -6 type sequence H description BINDING SITE FOR RESIDUE CD E 1592 source : DC9 13) chain E residue 474 type sequence E description BINDING SITE FOR RESIDUE CD F 1590 source : EC4 14) chain E residue 472 type sequence C description BINDING SITE FOR RESIDUE CL F 1591 source : EC5 15) chain E residue 477 type sequence M description BINDING SITE FOR RESIDUE CL F 1591 source : EC5 16) chain E residue 472 type sequence C description BINDING SITE FOR RESIDUE CL F 1593 source : EC7 17) chain E residue 472 type sequence C description BINDING SITE FOR RESIDUE CD F 1594 source : EC8 18) chain E residue 433 type sequence K description BINDING SITE FOR RESIDUE CL E 1593 source : FC1 19) chain E residue 434 type sequence P description BINDING SITE FOR RESIDUE CL E 1593 source : FC1 20) chain E residue 435 type sequence G description BINDING SITE FOR RESIDUE CL E 1593 source : FC1

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