eF-site ID 2w5e-C PDB Code 2w5e Chain C click to enlarge Title Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution Classification HYDROLASE Compound PUTATIVE SERINE PROTEASE Source Human astrovirus-1 (HAstV-1) (Q3ZN04_HASV1) Sequence C:  KHHHHHHIKPGALCVIDTPEGKGTGFFSGNDIVTAAHVVG NNTFVNVCYEGLMYEAKVRYMPEKDIAFITCPGDLHPTAR LKLSKNPDYSCVTVMAYVNEDLVVSTAAAMVYGNTLSYAV RTQDGMSGAPVCDKYCRVLAVHQTNTGYTGGAVIIDPTDF HP Description (1)  PUTATIVE SERINE PROTEASE Functional site 1) chain C residue 500 type sequence H description BINDING SITE FOR RESIDUE CL B 1589 source : AC9 2) chain C residue 500 type sequence H description BINDING SITE FOR RESIDUE CD B 1590 source : BC1 3) chain C residue -4 type sequence H description BINDING SITE FOR RESIDUE CD C 1587 source : BC6 4) chain C residue -2 type sequence H description BINDING SITE FOR RESIDUE CD C 1587 source : BC6 5) chain C residue -5 type sequence H description BINDING SITE FOR RESIDUE CL C 1588 source : BC7 6) chain C residue -4 type sequence H description BINDING SITE FOR RESIDUE CL C 1588 source : BC7 7) chain C residue -3 type sequence H description BINDING SITE FOR RESIDUE CL C 1588 source : BC7 8) chain C residue -3 type sequence H description BINDING SITE FOR RESIDUE CD C 1589 source : BC8 9) chain C residue -5 type sequence H description BINDING SITE FOR RESIDUE CD C 1589 source : BC8 10) chain C residue 515 type sequence C description BINDING SITE FOR RESIDUE CD C 1589 source : BC8 11) chain C residue 514 type sequence S description BINDING SITE FOR RESIDUE CL C 1590 source : BC9 12) chain C residue 515 type sequence C description BINDING SITE FOR RESIDUE CL C 1590 source : BC9 13) chain C residue -6 type sequence H description BINDING SITE FOR RESIDUE CL C 1591 source : CC1 14) chain C residue -6 type sequence H description BINDING SITE FOR RESIDUE CD C 1592 source : CC2 15) chain C residue 474 type sequence E description BINDING SITE FOR RESIDUE CD D 1589 source : CC5 16) chain C residue 446 type sequence K description BINDING SITE FOR RESIDUE CL C 1593 source : CC9 17) chain C residue 472 type sequence C description BINDING SITE FOR RESIDUE CD C 1594 source : DC1 18) chain C residue 472 type sequence C description BINDING SITE FOR RESIDUE CL D 1593 source : DC2 19) chain C residue 433 type sequence K description BINDING SITE FOR RESIDUE CL C 1595 source : DC3 20) chain C residue 434 type sequence P description BINDING SITE FOR RESIDUE CL C 1595 source : DC3 21) chain C residue 435 type sequence G description BINDING SITE FOR RESIDUE CL C 1595 source : DC3

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