eF-site ID 2w5e-B PDB Code 2w5e Chain B click to enlarge Title Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution Classification HYDROLASE Compound PUTATIVE SERINE PROTEASE Source Human astrovirus-1 (HAstV-1) (Q3ZN04_HASV1) Sequence B:  KHHHHHHIKPGALCVIDTPEGKGTGFFSGNDIVTAAHVVG NNTFVNVCYEGLMYEAKVRYMPEKDIAFITCPGDLHPTAR LKLSKNPDYSCVTVMAYVNEDLVVSTAAAMVYGNTLSYAV RTQDGMSGAPVCDKYCRVLAVHQTNTGYTGGAVIIDPTDF HP Description (1)  PUTATIVE SERINE PROTEASE Functional site 1) chain B residue 474 type sequence E description BINDING SITE FOR RESIDUE CD A 1589 source : AC3 2) chain B residue 472 type sequence C description BINDING SITE FOR RESIDUE CD A 1591 source : AC5 3) chain B residue 477 type sequence M description BINDING SITE FOR RESIDUE CD A 1591 source : AC5 4) chain B residue 472 type sequence C description BINDING SITE FOR RESIDUE CL A 1592 source : AC6 5) chain B residue 446 type sequence K description BINDING SITE FOR RESIDUE CL B 1587 source : AC7 6) chain B residue -5 type sequence H description BINDING SITE FOR RESIDUE CD B 1588 source : AC8 7) chain B residue -3 type sequence H description BINDING SITE FOR RESIDUE CD B 1588 source : AC8 8) chain B residue 515 type sequence C description BINDING SITE FOR RESIDUE CD B 1588 source : AC8 9) chain B residue -3 type sequence H description BINDING SITE FOR RESIDUE CL B 1589 source : AC9 10) chain B residue -4 type sequence H description BINDING SITE FOR RESIDUE CL B 1589 source : AC9 11) chain B residue -4 type sequence H description BINDING SITE FOR RESIDUE CD B 1590 source : BC1 12) chain B residue -2 type sequence H description BINDING SITE FOR RESIDUE CD B 1590 source : BC1 13) chain B residue -6 type sequence H description BINDING SITE FOR RESIDUE CL B 1591 source : BC2 14) chain B residue -6 type sequence H description BINDING SITE FOR RESIDUE CD A 1593 source : BC3 15) chain B residue -7 type sequence K description BINDING SITE FOR RESIDUE CD A 1593 source : BC3 16) chain B residue 514 type sequence S description BINDING SITE FOR RESIDUE CL B 1592 source : BC5 17) chain B residue 515 type sequence C description BINDING SITE FOR RESIDUE CL B 1592 source : BC5 18) chain B residue 500 type sequence H description BINDING SITE FOR RESIDUE CD E 1587 source : DC4 19) chain B residue 500 type sequence H description BINDING SITE FOR RESIDUE CL E 1588 source : DC5

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