eF-site ID 2w4m-A PDB Code 2w4m Chain A click to enlarge Title The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP Classification HYDROLASE Compound N-ACYLNEURAMINATE-9-PHOSPHATASE Source (NANP_HUMAN) Sequence A:  NLYFQSMGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKL LQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCITDLRTS HWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDV KAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAV VVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETD IQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELP ALLQSIDCKV Description Functional site 1) chain A residue 12 type sequence D description BINDING SITE FOR RESIDUE NA A1245 source : AC1 2) chain A residue 14 type sequence D description BINDING SITE FOR RESIDUE NA A1245 source : AC1 3) chain A residue 189 type sequence D description BINDING SITE FOR RESIDUE NA A1245 source : AC1 4) chain A residue 15 type sequence N description BINDING SITE FOR RESIDUE CL A1246 source : AC2 5) chain A residue 190 type sequence T description BINDING SITE FOR RESIDUE CL A1246 source : AC2 6) chain A residue 55 type sequence K description BINDING SITE FOR RESIDUE CL A1247 source : AC3 7) chain A residue 58 type sequence K description BINDING SITE FOR RESIDUE CL A1247 source : AC3 8) chain A residue 72 type sequence R description BINDING SITE FOR RESIDUE PO4 A1248 source : AC4 9) chain A residue 104 type sequence R description BINDING SITE FOR RESIDUE PO4 A1248 source : AC4 10) chain A residue 141 type sequence K description BINDING SITE FOR RESIDUE PO4 A1248 source : AC4 11) chain A residue 12 type sequence D description BINDING SITE FOR RESIDUE PO4 A1249 source : AC5 12) chain A residue 13 type sequence L description BINDING SITE FOR RESIDUE PO4 A1249 source : AC5 13) chain A residue 14 type sequence D description BINDING SITE FOR RESIDUE PO4 A1249 source : AC5 14) chain A residue 131 type sequence T description BINDING SITE FOR RESIDUE PO4 A1249 source : AC5 15) chain A residue 132 type sequence N description BINDING SITE FOR RESIDUE PO4 A1249 source : AC5 16) chain A residue 164 type sequence K description BINDING SITE FOR RESIDUE PO4 A1249 source : AC5 17) chain A residue 12 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 18) chain A residue 131 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 19) chain A residue 164 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI1

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