|
|
eF-site ID
|
2vxw-ABCD |
|
PDB Code
|
2vxw |
|
Chain
|
A, B, C, D |
|
click to enlarge
|
|
|
Title
|
Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-RANTES |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
C-C MOTIF CHEMOKINE 5 |
|
Source
|
Homo sapiens (Human) (CCL5_HUMAN) |
|
|
Sequence
|
A: |
FSPLSSQSSACCFAYIARPLPRAHIKEYFYTSGKCSNPAV
VFVTRKNRQVCANPEKKWVREYINSLEMS
|
| B: |
FSPLSSQSSACCFAYIARPLPRAHIKEYFYTSGKCSNPAV
VFVTRKNRQVCANPEKKWVREYINSLEMS
|
| C: |
QSSACCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRK
NRQVCANPEKKWVREYINSLEMS
|
| D: |
SSACCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKN
RQVCANPEKKWVREYINSLEMS
|
|
|
Description
|
(1) |
C-C MOTIF CHEMOKINE 5
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
10-51 |
| type |
prosite |
| sequence |
CCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQV
CA
|
| description |
SMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCFayiarp..LprahIkeYfytsgk..Csnp.AVVFvtrknrqv.CA
|
| source |
prosite : PS00472
|
|
|
2)
|
chain |
A |
| residue |
67 |
| type |
MOD_RES |
| sequence |
M
|
| description |
Methionine sulfoxide => ECO:0000269|PubMed:1380064
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
67 |
| type |
MOD_RES |
| sequence |
M
|
| description |
Methionine sulfoxide => ECO:0000269|PubMed:1380064
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
C |
| residue |
67 |
| type |
MOD_RES |
| sequence |
M
|
| description |
Methionine sulfoxide => ECO:0000269|PubMed:1380064
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
D |
| residue |
67 |
| type |
MOD_RES |
| sequence |
M
|
| description |
Methionine sulfoxide => ECO:0000269|PubMed:1380064
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|