eF-site ID 2vw5-D PDB Code 2vw5 Chain D click to enlarge Title Structure Of The Hsp90 Inhibitor 7-O-carbamoylpremacbecin Bound To The N- Terminus Of Yeast Hsp90 Classification CHAPERONE Compound ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (HSP82_YEAST) Sequence D:  MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASD ALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDS GIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQF GVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTL DEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEF VAYPIQLVVTKEVE Description Functional site 1) chain D residue 37 type sequence N description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 2) chain D residue 40 type sequence D description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 3) chain D residue 41 type sequence A description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 4) chain D residue 44 type sequence K description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 5) chain D residue 79 type sequence D description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 6) chain D residue 82 type sequence I description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 7) chain D residue 92 type sequence N description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 8) chain D residue 93 type sequence L description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 9) chain D residue 121 type sequence G description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 10) chain D residue 122 type sequence V description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 11) chain D residue 123 type sequence G description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 12) chain D residue 124 type sequence F description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 13) chain D residue 171 type sequence T description BINDING SITE FOR RESIDUE BC6 D 500 source : AC4 14) chain D residue 69 type sequence K description BINDING SITE FOR RESIDUE SO4 A1215 source : AC5 15) chain D residue 72 type sequence Q description BINDING SITE FOR RESIDUE SO4 A1215 source : AC5 16) chain D residue 65 type sequence R description BINDING SITE FOR RESIDUE SO4 D1215 source : AC7 17) chain D residue 78 type sequence R description BINDING SITE FOR RESIDUE SO4 D1215 source : AC7 18) chain D residue 165 type sequence E description BINDING SITE FOR RESIDUE SO4 D1215 source : AC7 19) chain D residue 102 type sequence K description BINDING SITE FOR RESIDUE SO4 A1216 source : BC1 20) chain D residue 98 type sequence K description BINDING SITE FOR RESIDUE SO4 D1216 source : BC2 21) chain D residue 99 type sequence S description BINDING SITE FOR RESIDUE SO4 D1216 source : BC2 22) chain D residue 33 type BINDING sequence E description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 23) chain D residue 84 type BINDING sequence M description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 24) chain D residue 92 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 25) chain D residue 98 type BINDING sequence K description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 26) chain D residue 99 type BINDING sequence S description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 27) chain D residue 171 type BINDING sequence T description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 28) chain D residue 37 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 29) chain D residue 79 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 30) chain D residue 119 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2

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