eF-site ID 2vw5-C PDB Code 2vw5 Chain C click to enlarge Title Structure Of The Hsp90 Inhibitor 7-O-carbamoylpremacbecin Bound To The N- Terminus Of Yeast Hsp90 Classification CHAPERONE Compound ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (HSP82_YEAST) Sequence C:  MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASD ALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDS GIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQF GVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTL DEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEF VAYPIQLVVTKEVE Description Functional site 1) chain C residue 37 type sequence N description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 2) chain C residue 40 type sequence D description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 3) chain C residue 41 type sequence A description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 4) chain C residue 44 type sequence K description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 5) chain C residue 79 type sequence D description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 6) chain C residue 82 type sequence I description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 7) chain C residue 92 type sequence N description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 8) chain C residue 93 type sequence L description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 9) chain C residue 121 type sequence G description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 10) chain C residue 122 type sequence V description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 11) chain C residue 123 type sequence G description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 12) chain C residue 124 type sequence F description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 13) chain C residue 171 type sequence T description BINDING SITE FOR RESIDUE BC6 C 500 source : AC3 14) chain C residue 78 type sequence R description BINDING SITE FOR RESIDUE SO4 C1215 source : AC6 15) chain C residue 165 type sequence E description BINDING SITE FOR RESIDUE SO4 C1215 source : AC6 16) chain C residue 98 type sequence K description BINDING SITE FOR RESIDUE SO4 C1216 source : AC8 17) chain C residue 99 type sequence S description BINDING SITE FOR RESIDUE SO4 C1216 source : AC8 18) chain C residue 69 type sequence K description BINDING SITE FOR RESIDUE SO4 B1215 source : AC9 19) chain C residue 102 type sequence K description BINDING SITE FOR RESIDUE SO4 B1216 source : BC3 20) chain C residue 33 type BINDING sequence E description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 21) chain C residue 84 type BINDING sequence M description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 22) chain C residue 92 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 23) chain C residue 98 type BINDING sequence K description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 24) chain C residue 99 type BINDING sequence S description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 25) chain C residue 171 type BINDING sequence T description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 26) chain C residue 37 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 27) chain C residue 79 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 28) chain C residue 119 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2

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