eF-site ID 2vw5-B PDB Code 2vw5 Chain B click to enlarge Title Structure Of The Hsp90 Inhibitor 7-O-carbamoylpremacbecin Bound To The N- Terminus Of Yeast Hsp90 Classification CHAPERONE Compound ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (HSP82_YEAST) Sequence B:  MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASD ALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDS GIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQF GVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTL DEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEF VAYPIQLVVTKEVE Description Functional site 1) chain B residue 37 type sequence N description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 2) chain B residue 40 type sequence D description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 3) chain B residue 41 type sequence A description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 4) chain B residue 79 type sequence D description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 5) chain B residue 82 type sequence I description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 6) chain B residue 88 type sequence E description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 7) chain B residue 92 type sequence N description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 8) chain B residue 93 type sequence L description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 9) chain B residue 121 type sequence G description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 10) chain B residue 122 type sequence V description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 11) chain B residue 123 type sequence G description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 12) chain B residue 124 type sequence F description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 13) chain B residue 171 type sequence T description BINDING SITE FOR RESIDUE BC6 B 500 source : AC2 14) chain B residue 69 type sequence K description BINDING SITE FOR RESIDUE SO4 C1215 source : AC6 15) chain B residue 72 type sequence Q description BINDING SITE FOR RESIDUE SO4 C1215 source : AC6 16) chain B residue 65 type sequence R description BINDING SITE FOR RESIDUE SO4 B1215 source : AC9 17) chain B residue 78 type sequence R description BINDING SITE FOR RESIDUE SO4 B1215 source : AC9 18) chain B residue 165 type sequence E description BINDING SITE FOR RESIDUE SO4 B1215 source : AC9 19) chain B residue 98 type sequence K description BINDING SITE FOR RESIDUE SO4 B1216 source : BC3 20) chain B residue 99 type sequence S description BINDING SITE FOR RESIDUE SO4 B1216 source : BC3 21) chain B residue 98 type BINDING sequence K description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 99 type BINDING sequence S description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 171 type BINDING sequence T description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 33 type BINDING sequence E description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 25) chain B residue 84 type BINDING sequence M description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 26) chain B residue 92 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 27) chain B residue 37 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 28) chain B residue 79 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 29) chain B residue 119 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2

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