eF-site ID 2vw5-A PDB Code 2vw5 Chain A click to enlarge Title Structure Of The Hsp90 Inhibitor 7-O-carbamoylpremacbecin Bound To The N- Terminus Of Yeast Hsp90 Classification CHAPERONE Compound ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (HSP82_YEAST) Sequence A:  MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASD ALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDS GIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQF GVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTL DEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEF VAYPIQLVVTKEVE Description Functional site 1) chain A residue 37 type sequence N description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 2) chain A residue 40 type sequence D description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 3) chain A residue 41 type sequence A description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 4) chain A residue 44 type sequence K description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 5) chain A residue 79 type sequence D description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 6) chain A residue 82 type sequence I description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 7) chain A residue 92 type sequence N description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 8) chain A residue 93 type sequence L description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 9) chain A residue 98 type sequence K description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 10) chain A residue 121 type sequence G description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 11) chain A residue 122 type sequence V description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 12) chain A residue 123 type sequence G description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 13) chain A residue 124 type sequence F description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 14) chain A residue 171 type sequence T description BINDING SITE FOR RESIDUE BC6 A 500 source : AC1 15) chain A residue 65 type sequence R description BINDING SITE FOR RESIDUE SO4 A1215 source : AC5 16) chain A residue 78 type sequence R description BINDING SITE FOR RESIDUE SO4 A1215 source : AC5 17) chain A residue 165 type sequence E description BINDING SITE FOR RESIDUE SO4 A1215 source : AC5 18) chain A residue 69 type sequence K description BINDING SITE FOR RESIDUE SO4 D1215 source : AC7 19) chain A residue 72 type sequence Q description BINDING SITE FOR RESIDUE SO4 D1215 source : AC7 20) chain A residue 98 type sequence K description BINDING SITE FOR RESIDUE SO4 A1216 source : BC1 21) chain A residue 99 type sequence S description BINDING SITE FOR RESIDUE SO4 A1216 source : BC1 22) chain A residue 102 type sequence K description BINDING SITE FOR RESIDUE SO4 D1216 source : BC2 23) chain A residue 149 type sequence E description BINDING SITE FOR RESIDUE SO4 A1217 source : BC4 24) chain A residue 151 type sequence N description BINDING SITE FOR RESIDUE SO4 A1217 source : BC4 25) chain A residue 155 type sequence S description BINDING SITE FOR RESIDUE SO4 A1217 source : BC4 26) chain A residue 156 type sequence F description BINDING SITE FOR RESIDUE SO4 A1217 source : BC4 27) chain A residue 157 type sequence T description BINDING SITE FOR RESIDUE SO4 A1217 source : BC4 28) chain A residue 33 type BINDING sequence E description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 29) chain A residue 84 type BINDING sequence M description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 30) chain A residue 92 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 31) chain A residue 98 type BINDING sequence K description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 99 type BINDING sequence S description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 33) chain A residue 171 type BINDING sequence T description BINDING => ECO:0000269|PubMed:16625188, ECO:0007744|PDB:2CG9 source Swiss-Prot : SWS_FT_FI1 34) chain A residue 37 type BINDING sequence N description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 35) chain A residue 79 type BINDING sequence D description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 36) chain A residue 119 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:16625188, ECO:0000269|PubMed:9230303, ECO:0007744|PDB:1AM1, ECO:0007744|PDB:1AMW, ECO:0007744|PDB:2CG9, ECO:0007744|PDB:2WEP source Swiss-Prot : SWS_FT_FI2 37) chain A residue 24-33 type prosite sequence YSNKEIFLRE description HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE source prosite : PS00298

Display surface Download Links