eF-site ID 2vv3-AB PDB Code 2vv3 Chain A, B click to enlarge Title hPPARgamma Ligand binding domain in complex with 4-oxoDHA Classification RECEPTOR Compound PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA Source (PPARG_HUMAN) Sequence A:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTDKSPF VIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITE YAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDG VLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALE LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKK TETDMSLHPLLQEIYKD B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFV IYDMNSLMMGEDKIEVAIRIFQGCQFRSVEAVQEITEYAK SIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLI SEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDD SDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQL KLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTPL LQEIYK Description Functional site 1) chain A residue 284 type sequence G description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 2) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 3) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 4) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 5) chain A residue 323 type sequence H description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 6) chain A residue 327 type sequence Y description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 7) chain A residue 340 type sequence L description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 8) chain A residue 341 type sequence I description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 9) chain A residue 342 type sequence S description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 10) chain A residue 367 type sequence K description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 11) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 12) chain A residue 469 type sequence L description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 13) chain A residue 473 type sequence Y description BINDING SITE FOR RESIDUE 4R8 A 1476 source : AC1 14) chain A residue 316 type BINDING sequence T description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 15) chain A residue 353 type BINDING sequence L description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 16) chain B residue 316 type BINDING sequence T description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 17) chain B residue 353 type BINDING sequence L description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 18) chain A residue 254 type CROSSLNK sequence S description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2 19) chain B residue 254 type CROSSLNK sequence S description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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