eF-site ID 2vv0-B
PDB Code 2vv0
Chain B

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Title hPPARgamma Ligand binding domain in complex with DHA
Classification RECEPTOR
Compound PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
Source (PPARG_HUMAN)
Sequence B:  SADLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFVI
YDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYA
KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVL
ISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELD
DSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTE
THPLLQEIYKDL
Description


Functional site

1) chain B
residue 281
type
sequence I
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

2) chain B
residue 285
type
sequence C
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

3) chain B
residue 288
type
sequence R
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

4) chain B
residue 326
type
sequence I
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

5) chain B
residue 330
type
sequence L
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

6) chain B
residue 333
type
sequence L
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

7) chain B
residue 341
type
sequence I
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

8) chain B
residue 342
type
sequence S
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

9) chain B
residue 348
type
sequence M
description BINDING SITE FOR RESIDUE HXA B 1477
source : AC2

10) chain B
residue 316
type BINDING
sequence T
description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
source Swiss-Prot : SWS_FT_FI1

11) chain B
residue 353
type BINDING
sequence L
description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
source Swiss-Prot : SWS_FT_FI1

12) chain B
residue 254
type CROSSLNK
sequence S
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
source Swiss-Prot : SWS_FT_FI2


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