|
|
eF-site ID
|
2voi-AB |
|
PDB Code
|
2voi |
|
Chain
|
A, B |
|
click to enlarge
|
|
|
Title
|
Structure of mouse A1 bound to the Bid BH3-domain |
|
Classification
|
APOPTOSIS |
|
Compound
|
BCL-2-RELATED PROTEIN A1 |
|
Source
|
null (BID_MOUSE) |
|
|
Sequence
|
A: |
SMAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQR
VAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEF
EDGIINWGRIVTIFAFGGVLLKKLKQEQIALDVSAYKQVS
SFVAEFIMNNTGEWIRQNGGWEDGFIKKFE
|
| B: |
SQEEIIHNIARHLAQIGDEMDHNI
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE CL A1150
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
98 |
| type |
SITE |
| sequence |
D
|
| description |
Cleavage => ECO:0000269|PubMed:9873064
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
78 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P55957
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
78-97 |
| type |
prosite |
| sequence |
EFEDGIINWGRIVTIFAFGG
|
| description |
BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. EFeDGiiNWGRIVTIFaFGG
|
| source |
prosite : PS01080
|
|
|
5)
|
chain |
A |
| residue |
133-144 |
| type |
prosite |
| sequence |
WIRQNGGWEDGF
|
| description |
BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIrqnGGWEdGF
|
| source |
prosite : PS01258
|
|
|
6)
|
chain |
B |
| residue |
86-100 |
| type |
prosite |
| sequence |
IARHLAQIGDEMDHN
|
| description |
BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. IarhLAqIGDEMDHN
|
| source |
prosite : PS01259
|
|
|
|