eF-site ID 2voh-A
PDB Code 2voh
Chain A

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Title Structure of mouse A1 bound to the Bak BH3-domain
Classification APOPTOSIS
Compound BCL-2-RELATED PROTEIN A1
Source Mus musculus (Mouse) (BAK_MOUSE)
Sequence A:  GPLGSMAESELMHIHSLAEHYLQYVLQVPAFESAPSQACR
VLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVM
EKEFEDGIINWGRIVTIFAFGGVLLKKLKQEQIALDVSAY
KQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEP
Description


Functional site

1) chain A
residue 42
type
sequence F
description BINDING SITE FOR RESIDUE SO4 B1088
source : AC1

2) chain A
residue 46
type
sequence K
description BINDING SITE FOR RESIDUE SO4 B1088
source : AC1

3) chain A
residue 77
type
sequence K
description BINDING SITE FOR RESIDUE SO4 B1088
source : AC1

4) chain A
residue 5
type
sequence E
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

5) chain A
residue 8
type
sequence H
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

6) chain A
residue 138
type
sequence G
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

7) chain A
residue 139
type
sequence G
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

8) chain A
residue 140
type
sequence W
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

9) chain A
residue 141
type
sequence E
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

10) chain A
residue 142
type
sequence D
description BINDING SITE FOR RESIDUE CIT A1151
source : AC2

11) chain A
residue 78-97
type prosite
sequence EFEDGIINWGRIVTIFAFGG
description BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. EFeDGiiNWGRIVTIFaFGG
source prosite : PS01080

12) chain A
residue 133-144
type prosite
sequence WIRQNGGWEDGF
description BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIrqnGGWEdGF
source prosite : PS01258


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