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eF-site ID
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2vlr-F |
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PDB Code
|
2vlr |
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Chain
|
F |
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click to enlarge
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Title
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The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain |
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Classification
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IMMUNE SYSTEM |
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Compound
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HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN |
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Source
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(2VLR) |
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Sequence
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F: |
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA
ASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGT
LRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDG
KDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYL
EGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT
FQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
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Description
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(1) |
HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, JM22 TCR ALPHA CHAIN, JM22 TCR BETA CHAIN
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Functional site
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1)
|
chain |
F |
| residue |
143 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
F |
| residue |
146 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
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| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
F |
| residue |
171 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
|
chain |
F |
| residue |
7 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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5)
|
chain |
F |
| residue |
73 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
F |
| residue |
84 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
F |
| residue |
116 |
| type |
CARBOHYD |
| sequence |
Y
|
| description |
N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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8)
|
chain |
F |
| residue |
159 |
| type |
CARBOHYD |
| sequence |
Y
|
| description |
N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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9)
|
chain |
F |
| residue |
86 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI4
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