eF-site ID 2vkx-ABCDEF PDB Code 2vkx Chain A, B, C, D, E, F click to enlarge Title Human NCAM, FN3 domains 1 and 2, M610R mutant Classification CELL ADHESION Compound NEURAL CELL ADHESION MOLECULE Source (NCA11_HUMAN) Sequence A:  ADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAE WRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRL AALNGKGLGEISAASEFKTQPVREPSAPKLEGQRGEDGNS IKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSD HVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTAAAH B:  ADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAE WRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRL AALNGKGLGEISAASEFKTQPVREPSAPKLEGQRGEDGNS IKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSD HVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTAAA C:  ADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAE WRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRL AALNGKGLGEISAASEFKTQPVREPSAPKLEGQRGEDGNS IKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSD HVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTAAAH D:  ADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAE WRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRL AALNGKGLGEISAASEFKTQPVREPSAPKLEGQRGEDGNS IKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSD HVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTAAAH E:  APLAQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPIL KYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETT YAVRLAALNGKGLGEISAASEFKTQPVREPSAPKLEGQRG EDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRL PSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRT AAA F:  ADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAE WRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRL AALNGKGLGEISAASEFKTQPVREPSAPKLEGQRGEDGNS IKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSD HVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTAAAH Description (1)  NEURAL CELL ADHESION MOLECULE Functional site 1) chain A residue 546 type sequence H description BINDING SITE FOR RESIDUE SO4 A1696 source : AC1 2) chain A residue 547 type sequence S description BINDING SITE FOR RESIDUE SO4 A1696 source : AC1 3) chain A residue 646 type sequence K description BINDING SITE FOR RESIDUE SO4 A1696 source : AC1 4) chain A residue 664 type sequence D description BINDING SITE FOR RESIDUE SO4 A1696 source : AC1 5) chain C residue 539 type sequence A description BINDING SITE FOR RESIDUE SO4 C1696 source : AC2 6) chain C residue 546 type sequence H description BINDING SITE FOR RESIDUE SO4 C1696 source : AC2 7) chain C residue 567 type sequence K description BINDING SITE FOR RESIDUE SO4 C1696 source : AC2 8) chain C residue 572 type sequence Y description BINDING SITE FOR RESIDUE SO4 C1696 source : AC2 9) chain C residue 639 type sequence R description BINDING SITE FOR RESIDUE SO4 C1697 source : AC3 10) chain C residue 641 type sequence L description BINDING SITE FOR RESIDUE SO4 C1697 source : AC3 11) chain C residue 642 type sequence S description BINDING SITE FOR RESIDUE SO4 C1697 source : AC3 12) chain E residue 569 type sequence E description BINDING SITE FOR RESIDUE SO4 C1697 source : AC3 13) chain E residue 571 type sequence T description BINDING SITE FOR RESIDUE SO4 C1697 source : AC3 14) chain D residue 569 type sequence E description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 15) chain D residue 570 type sequence T description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 16) chain D residue 571 type sequence T description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 17) chain D residue 594 type sequence K description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 18) chain F residue 639 type sequence R description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 19) chain F residue 641 type sequence L description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 20) chain F residue 642 type sequence S description BINDING SITE FOR RESIDUE SO4 F1696 source : AC4 21) chain F residue 692 type sequence A description BINDING SITE FOR RESIDUE SO4 F1697 source : AC5 22) chain F residue 693 type sequence A description BINDING SITE FOR RESIDUE SO4 F1697 source : AC5 23) chain A residue 692 type sequence A description BINDING SITE FOR RESIDUE SO4 A1697 source : AC6 24) chain A residue 693 type sequence A description BINDING SITE FOR RESIDUE SO4 A1697 source : AC6 25) chain D residue 650 type sequence R description BINDING SITE FOR RESIDUE SO4 F1698 source : AC7 26) chain F residue 538 type sequence R description BINDING SITE FOR RESIDUE SO4 F1698 source : AC7 27) chain F residue 539 type sequence A description BINDING SITE FOR RESIDUE SO4 F1698 source : AC7 28) chain F residue 542 type sequence E description BINDING SITE FOR RESIDUE SO4 F1698 source : AC7 29) chain F residue 546 type sequence H description BINDING SITE FOR RESIDUE SO4 F1698 source : AC7 30) chain F residue 572 type sequence Y description BINDING SITE FOR RESIDUE SO4 F1698 source : AC7 31) chain A residue 538 type sequence R description BINDING SITE FOR RESIDUE SO4 E1695 source : AC8 32) chain E residue 666 type sequence N description BINDING SITE FOR RESIDUE SO4 E1695 source : AC8 33) chain E residue 690 type sequence R description BINDING SITE FOR RESIDUE SO4 E1695 source : AC8 34) chain D residue 692 type sequence A description BINDING SITE FOR RESIDUE SO4 D1696 source : AC9 35) chain D residue 693 type sequence A description BINDING SITE FOR RESIDUE SO4 D1696 source : AC9 36) chain B residue 652 type sequence P description BINDING SITE FOR RESIDUE SO4 F1699 source : BC1 37) chain F residue 643 type sequence S description BINDING SITE FOR RESIDUE SO4 F1699 source : BC1 38) chain F residue 646 type sequence K description BINDING SITE FOR RESIDUE SO4 F1699 source : BC1 39) chain F residue 632 type sequence R description BINDING SITE FOR RESIDUE SO4 F1700 source : BC2 40) chain F residue 633 type sequence H description BINDING SITE FOR RESIDUE SO4 F1700 source : BC2 41) chain F residue 650 type sequence R description BINDING SITE FOR RESIDUE SO4 F1700 source : BC2

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