eF-site ID 2vgc-C PDB Code 2vgc Chain C click to enlarge Title GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX Classification SERINE PROTEASE Compound GAMMA CHYMOTRYPSIN Source ORGANISM_COMMON: cattle; ORGANISM_SCIENTIFIC: Bos taurus; Sequence C:  TPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSS CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYAR VTALVNWVQQTLAAN Description Functional site 1) chain C residue 195 type sequence S description THE CATALYTIC SITE WHICH INCLUDES THE INHIBITOR PATCHED TO SERINE 195 AND HISTIDINE 57. source : CAT 2) chain C residue 153 type sequence D description BINDING SITE FOR RESIDUE SO4 C 357 source : AC1 3) chain C residue 154 type sequence R description BINDING SITE FOR RESIDUE SO4 C 357 source : AC1 4) chain C residue 237 type sequence W description BINDING SITE FOR RESIDUE SO4 B 358 source : AC2 5) chain C residue 190 type sequence S description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 6) chain C residue 195 type sequence S description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 7) chain C residue 213 type sequence V description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 8) chain C residue 214 type sequence S description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 9) chain C residue 215 type sequence W description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 10) chain C residue 216 type sequence G description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 11) chain C residue 217 type sequence S description BINDING SITE FOR RESIDUE V35 C 358 source : AC3 12) chain C residue 193 type catalytic sequence G description 387 source MCSA : MCSA1 13) chain C residue 195 type catalytic sequence S description 387 source MCSA : MCSA1 14) chain C residue 196 type catalytic sequence G description 387 source MCSA : MCSA1 15) chain C residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 16) chain C residue 189-200 type prosite sequence SSCMGDSGGPLV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV source prosite : PS00135

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