eF-site ID 2ve7-ABCD PDB Code 2ve7 Chain A, B, C, D click to enlarge Title Crystal structure of a bonsai version of the human Ndc80 complex Classification CELL CYCLE Compound KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25 Source Homo sapiens (Human) (SPC24_HUMAN) Sequence A:  MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQ APSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDL GYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAM KESSGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMN AELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQERS TANKANAERLKRLQKSADLYKDRLGLEIRFTNINPESPFR KAFTAT B:  MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQ APSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDL GYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAM KESSWGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEM NAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQER STANKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFI FTNIDPKNPESPFMFSLHLNEARDYEVSDSAGLAEFQENV RKTNNFSAFLANVRKAFTATVYQ C:  LSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPE VLHMIYMRALQIVYGIRLEHFYMMPVNSGVMYPHLMEGFL PFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSG IINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEAL MKLEIPSAVYVAQLYHQVSKIEWEYECEPGMVKGIHQPIH LDSTQLSRKFISDYLWSLV D:  LSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPE VLHMIYMRALQIVYGIRLEHFYMMPVNSGVMYPHLMEGFL PFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSG IINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEAL MKLERLEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWEYEC EPGMVKGIHHGPSVAQPIHLDSTQLSRKFISDYLWSLVDT EW Description Functional site 1) chain A residue 228 type sequence Y description BINDING SITE FOR RESIDUE IPH C2194 source : AC1 2) chain C residue 134 type sequence C description BINDING SITE FOR RESIDUE IPH C2194 source : AC1 3) chain C residue 137 type sequence T description BINDING SITE FOR RESIDUE IPH C2194 source : AC1 4) chain D residue 19 type sequence R description BINDING SITE FOR RESIDUE IPH C2194 source : AC1 5) chain B residue 228 type sequence Y description BINDING SITE FOR RESIDUE IPH D2198 source : AC2 6) chain B residue 243 type sequence F description BINDING SITE FOR RESIDUE IPH D2198 source : AC2 7) chain C residue 19 type sequence R description BINDING SITE FOR RESIDUE IPH D2198 source : AC2 8) chain D residue 133 type sequence A description BINDING SITE FOR RESIDUE IPH D2198 source : AC2 9) chain D residue 134 type sequence C description BINDING SITE FOR RESIDUE IPH D2198 source : AC2 10) chain D residue 137 type sequence T description BINDING SITE FOR RESIDUE IPH D2198 source : AC2 11) chain A residue 199 type sequence K description BINDING SITE FOR RESIDUE GOL B2225 source : AC3 12) chain A residue 200 type sequence E description BINDING SITE FOR RESIDUE GOL B2225 source : AC3 13) chain B residue 120 type sequence P description BINDING SITE FOR RESIDUE GOL B2225 source : AC3 14) chain B residue 171 type sequence T description BINDING SITE FOR RESIDUE GOL B2225 source : AC3 15) chain B residue 172 type sequence V description BINDING SITE FOR RESIDUE GOL B2225 source : AC3 16) chain B residue 173 type sequence G description BINDING SITE FOR RESIDUE GOL B2225 source : AC3 17) chain A residue 120 type sequence P description BINDING SITE FOR RESIDUE GOL A2222 source : AC4 18) chain A residue 121 type sequence S description BINDING SITE FOR RESIDUE GOL A2222 source : AC4 19) chain A residue 172 type sequence V description BINDING SITE FOR RESIDUE GOL A2222 source : AC4 20) chain A residue 173 type sequence G description BINDING SITE FOR RESIDUE GOL A2222 source : AC4 21) chain B residue 135 type sequence F description BINDING SITE FOR RESIDUE GOL A2222 source : AC4 22) chain A residue 242 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q9D0F1 source Swiss-Prot : SWS_FT_FI2 23) chain B residue 242 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q9D0F1 source Swiss-Prot : SWS_FT_FI2

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