eF-site ID 2vcq-D PDB Code 2vcq Chain D click to enlarge Title Complex structure of prostaglandin D2 synthase at 1.95A. Classification ISOMERASE Compound GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE Source Homo sapiens (Human) (PTGD2_HUMAN) Sequence D:  PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE IKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNT EMEQCHVDAIVDTLDDFMQDVKEQMFNELLTYNAPHLMQD LDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN HPRLVTLRKKVQAIPAVANWIKRRPQTKL Description Functional site 1) chain D residue 97 type sequence D description BINDING SITE FOR RESIDUE GSH C1200 source : AC3 2) chain D residue 8 type sequence Y description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 3) chain D residue 14 type sequence R description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 4) chain D residue 39 type sequence W description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 5) chain D residue 43 type sequence K description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 6) chain D residue 50 type sequence K description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 7) chain D residue 51 type sequence I description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 8) chain D residue 52 type sequence P description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 9) chain D residue 63 type sequence Q description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 10) chain D residue 64 type sequence S description BINDING SITE FOR RESIDUE GSH D1200 source : AC4 11) chain D residue 8 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:18341273, ECO:0000269|PubMed:19939518 source Swiss-Prot : SWS_FT_FI1 12) chain D residue 14 type BINDING sequence R description BINDING => ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:18341273, ECO:0000269|PubMed:19939518 source Swiss-Prot : SWS_FT_FI1 13) chain D residue 39 type BINDING sequence W description BINDING => ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:18341273, ECO:0000269|PubMed:19939518 source Swiss-Prot : SWS_FT_FI1 14) chain D residue 49 type BINDING sequence G description BINDING => ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:18341273, ECO:0000269|PubMed:19939518 source Swiss-Prot : SWS_FT_FI1 15) chain D residue 63 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:18341273, ECO:0000269|PubMed:19939518 source Swiss-Prot : SWS_FT_FI1

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