eF-site ID 2vbl-AB PDB Code 2vbl Chain A, B click to enlarge Title Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers Classification HYDROLASE Compound DNA ENDONUCLEASE I-CREI Source Chlamydomonas reinhardtii (Chlamydomonas smithii) (2VBL) Sequence A:  NTKYNKEFLLYLAGFVDGDGSIIAQIEPNASYKFKHRLKL TFKVTQKTQRRWFLDKLVDEIGVGYVRDEGSVSNYILSEI KPLRNFLTQLQPFLKLKQKQANLVLKITEQLPSAKESPDK FLEVCTWVDQIAALNDSKTRKTTSETVRAVLD B:  NTKYNKEFLLYLAGFVDADGSIIAQIAPNQSSKFKHRLKL TFQVTQKTQRRWFLDKLVDEIGVGYVRGSGSVSNYILSEI KPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDK FLEVCTWVDQIAALNDSKTRKTTSETVRAVLD Description Functional site 1) chain A residue 19 type sequence G description BINDING SITE FOR RESIDUE MG C 1025 source : AC1 2) chain B residue 20 type sequence D description BINDING SITE FOR RESIDUE MG C 1025 source : AC1 3) chain A residue 20 type sequence D description BINDING SITE FOR RESIDUE MG C 1026 source : AC2 4) chain B residue 20 type sequence D description BINDING SITE FOR RESIDUE MG C 1026 source : AC2 5) chain A residue 20 type sequence D description BINDING SITE FOR RESIDUE MG E 1025 source : AC3 6) chain B residue 19 type sequence A description BINDING SITE FOR RESIDUE MG E 1025 source : AC3 7) chain B residue 19 type catalytic sequence A description 233 source MCSA : MCSA1 8) chain B residue 20 type catalytic sequence D description 233 source MCSA : MCSA1 9) chain B residue 19 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI1 10) chain B residue 20 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1

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