eF-site ID 2v87-E
PDB Code 2v87
Chain E

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Title Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me3 peptide
Classification PROTEIN BINDING
Compound VDJ RECOMBINATION-ACTIVATING PROTEIN 2
Source (H32_MOUSE)
Sequence E:  AXTXQTARKSTGG
Description


Functional site

1) chain E
residue 5
type MOD_RES
sequence Q
description 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
source Swiss-Prot : SWS_FT_FI4

2) chain E
residue 6
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000250|UniProtKB:Q71DI3
source Swiss-Prot : SWS_FT_FI5

3) chain E
residue 8
type MOD_RES
sequence R
description Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000269|PubMed:15485929
source Swiss-Prot : SWS_FT_FI6

4) chain E
residue 9
type MOD_RES
sequence K
description N6-methyllysine; alternate => ECO:0000269|PubMed:13678296, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI7

5) chain E
residue 2
type MOD_RES
sequence X
description Citrulline; alternate => ECO:0000269|PubMed:15339660
source Swiss-Prot : SWS_FT_FI1

6) chain E
residue 3
type MOD_RES
sequence T
description Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610
source Swiss-Prot : SWS_FT_FI2

7) chain E
residue 4
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI3

8) chain E
residue 10
type MOD_RES
sequence S
description Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15735677, ECO:0000269|PubMed:15870105
source Swiss-Prot : SWS_FT_FI8

9) chain E
residue 11
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000250|UniProtKB:P68431
source Swiss-Prot : SWS_FT_FI9


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