eF-site ID 2v6j-A
PDB Code 2v6j
Chain A

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Title Kokobera Virus Helicase: Mutant Met47Thr
Classification HYDROLASE
Compound RNA HELICASE
Source Kokobera virus (KOKV) (Q32ZD5_9FLAV)
Sequence A:  RELTVLDLHPGAGKTRRVLPQLVREAVKKRLRTVILAPTR
VVASETYEALRGEPIRYMGNEIVDFMCHSTFTMKLLQGVR
VPNYNLYIMDEAHFLDPASVAARGYIETRVSMGDAGAIFM
TATPPGTTEAFPPSNSPIIDEETRIPDKAWNSGYEWITEF
DGRTVWFVHSIKQGAEIGTCLQKAGKKVLYLNRKTFESEY
PKCKSEKWDFVITTDISEMGANFKADRVIDPRKTIKPILL
DGRVSMQGPIAITPASAAQRRGRIGRNPEKLGDIYAYSGN
VSSDNEGHVSWTEARMLLDNVHVQGGVVAQLYTPEREKTE
AYEGEFKLKTNQRKVFSELIRTGDLPVWLAFQVASANVEY
HDRKWCFDGPNEHLLLENNQEIEVWTRQGQRRVLKPRWLD
GRITSDHLNLKSFKEFASGKR
Description


Functional site
1) chain A
residue 270
type SITE
sequence R
description Involved in NS3 ATPase and RTPase activities => ECO:0000250|UniProtKB:P14335
source Swiss-Prot : SWS_FT_FI3
2) chain A
residue 431
type SITE
sequence R
description Cleavage; by autolysis => ECO:0000250|UniProtKB:P06935
source Swiss-Prot : SWS_FT_FI4
3) chain A
residue 9
type BINDING
sequence L
description BINDING => ECO:0000255|PROSITE-ProRule:PRU00541
source Swiss-Prot : SWS_FT_FI1
4) chain A
residue 15
type SITE
sequence K
description Substrate binding => ECO:0000269|PubMed:18004778
source Swiss-Prot : SWS_FT_FI2
5) chain A
residue 273
type SITE
sequence R
description Substrate binding => ECO:0000269|PubMed:18004778
source Swiss-Prot : SWS_FT_FI2
6) chain A
residue 276
type SITE
sequence R
description Substrate binding => ECO:0000269|PubMed:18004778
source Swiss-Prot : SWS_FT_FI2

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