|
|
eF-site ID
|
2v5l-B |
|
PDB Code
|
2v5l |
|
Chain
|
B |
|
click to enlarge
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Title
|
Structures of the Open and Closed State of Trypanosomal Triosephosphate Isomerase: as Observed in a New Crystal Form: Implications for the Reaction Mechanism |
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Classification
|
OXIDOREDUCTASE |
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Compound
|
TRIOSEPHOSPHATE ISOMERASE |
|
Source
|
null (TPIS_TRYBB) |
|
|
Sequence
|
B: |
SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVV
ASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLP
ILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF
MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAK
VVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGAD
VAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE
FVDIIKATQ
|
|
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Description
|
(1) |
TRIOSEPHOSPHATE ISOMERASE (E.C.5.3.1.1)
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
535 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE SO4 B 1551
|
| source |
: AC2
|
|
|
2)
|
chain |
B |
| residue |
395 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
467 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
311 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
B |
| residue |
313 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|