eF-site ID 2v30-B PDB Code 2v30 Chain B click to enlarge Title Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP. Classification LYASE Compound OROTIDINE 5'-PHOSPHATE DECARBOXYLASE Source Homo sapiens (Human) (PYR5_HUMAN) Sequence B:  MELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSL ARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLA KCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNA HVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDY TRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLE AGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEA AEMYRKAAWEAYLSRL Description Functional site 1) chain B residue 317 type sequence D description BINDING SITE FOR RESIDUE U5P A1480 source : AC1 2) chain B residue 318 type sequence I description BINDING SITE FOR RESIDUE U5P A1480 source : AC1 3) chain B residue 321 type sequence T description BINDING SITE FOR RESIDUE U5P A1480 source : AC1 4) chain B residue 257 type sequence S description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 5) chain B residue 259 type sequence D description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 6) chain B residue 281 type sequence K description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 7) chain B residue 283 type sequence H description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 8) chain B residue 312 type sequence D description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 9) chain B residue 314 type sequence K description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 10) chain B residue 371 type sequence M description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 11) chain B residue 372 type sequence S description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 12) chain B residue 417 type sequence P description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 13) chain B residue 430 type sequence Q description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 14) chain B residue 432 type sequence Y description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 15) chain B residue 450 type sequence G description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 16) chain B residue 451 type sequence R description BINDING SITE FOR RESIDUE U5P B1479 source : AC2 17) chain B residue 312 type ACT_SITE sequence D description For OMPdecase activity => ECO:0000269|PubMed:18184586 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 314 type ACT_SITE sequence K description For OMPdecase activity => ECO:0000269|PubMed:18184586 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 317 type ACT_SITE sequence D description For OMPdecase activity => ECO:0000269|PubMed:18184586 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 281 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCL source Swiss-Prot : SWS_FT_FI4 21) chain B residue 314 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCL source Swiss-Prot : SWS_FT_FI4 22) chain B residue 257 type BINDING sequence S description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD source Swiss-Prot : SWS_FT_FI2 23) chain B residue 317 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD source Swiss-Prot : SWS_FT_FI2 24) chain B residue 321 type BINDING sequence T description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD source Swiss-Prot : SWS_FT_FI2 25) chain B residue 259 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD, ECO:0007744|PDB:2QCH source Swiss-Prot : SWS_FT_FI3 26) chain B residue 372 type BINDING sequence S description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD, ECO:0007744|PDB:2QCH source Swiss-Prot : SWS_FT_FI3 27) chain B residue 430 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD, ECO:0007744|PDB:2QCH source Swiss-Prot : SWS_FT_FI3 28) chain B residue 450 type BINDING sequence G description BINDING => ECO:0000269|PubMed:18184586, ECO:0007744|PDB:2QCD, ECO:0007744|PDB:2QCH source Swiss-Prot : SWS_FT_FI3

Display surface Download Links