|
eF-site ID
|
2uzu-I |
PDB Code
|
2uzu |
Chain
|
I |
|
click to enlarge
|
|
Title
|
PKA structures of indazole-pyridine series of AKT inhibitors |
Classification
|
TRANSFERASE |
Compound
|
CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT |
Source
|
Bos taurus (Bovine) (IPKA_BOVIN) |
|
Sequence
|
I: |
TTYADFIASGRTGRRNAIHD
|
|
Description
|
(1) |
CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT (E.C.2.7.11.11), CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA
|
|
Functional site
|
|
1)
|
chain |
I |
residue |
16 |
type |
SITE |
sequence |
T
|
description |
Important for inhibition => ECO:0000250
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
I |
residue |
19 |
type |
SITE |
sequence |
R
|
description |
Important for inhibition => ECO:0000250
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
I |
residue |
20 |
type |
SITE |
sequence |
N
|
description |
Important for inhibition => ECO:0000250
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|