|
|
eF-site ID
|
2uzi-H |
|
PDB Code
|
2uzi |
|
Chain
|
H |
|
click to enlarge
|
|
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Title
|
Crystal structure of HRAS(G12V) - anti-RAS Fv complex |
|
Classification
|
SIGNALING PROTEIN/IMMUNE SYSTEM |
|
Compound
|
ANTI-RAS FV HEAVY CHAIN |
|
Source
|
Homo sapiens (Human) (RASH_HUMAN) |
|
|
Sequence
|
H: |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSTFSMNWVRQA
PGKGLEWVSYISRTSKTIYYADSVKGRFTISRDNSKNTLY
LQMNSLRAEDTAVYYCARGRFFDYWGQGTLVTVS
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
H |
| residue |
73 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE ZN H1115
|
| source |
: AC1
|
|
|
2)
|
chain |
H |
| residue |
75 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE ZN H1115
|
| source |
: AC1
|
|
|
3)
|
chain |
H |
| residue |
62 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE ZN H1116
|
| source |
: AC2
|
|
|
4)
|
chain |
H |
| residue |
1 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE ZN R1171
|
| source |
: AC6
|
|
|
|