eF-site ID 2uyz-A
PDB Code 2uyz
Chain A

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Title Non-covalent complex between Ubc9 and SUMO1
Classification LIGASE
Compound SUMO-CONJUGATING ENZYME UBC9
Source Mus musculus (Mouse) (SUMO1_HUMAN)
Sequence A:  GIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWE
CAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLF
HPNVYPSGTVSLSILEEDKDWRPAITIKQILLGIQELLNE
PNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
Description


Functional site

1) chain A
residue 87
type
sequence Y
description BINDING SITE FOR RESIDUE NA A1159
source : AC1

2) chain A
residue 93
type
sequence S
description BINDING SITE FOR RESIDUE NA A1159
source : AC1

3) chain A
residue 98
type
sequence E
description BINDING SITE FOR RESIDUE NA A1159
source : AC1

4) chain A
residue 18
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P63279
source Swiss-Prot : SWS_FT_FI7

5) chain A
residue 48
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P63279
source Swiss-Prot : SWS_FT_FI8

6) chain A
residue 101
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P63279
source Swiss-Prot : SWS_FT_FI8

7) chain A
residue 49
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:P63279
source Swiss-Prot : SWS_FT_FI9

8) chain A
residue 71
type MOD_RES
sequence S
description Phosphoserine; by CDK1 => ECO:0000250|UniProtKB:P63279
source Swiss-Prot : SWS_FT_FI6

9) chain A
residue 93
type ACT_SITE
sequence S
description Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
source Swiss-Prot : SWS_FT_FI1

10) chain A
residue 100
type SITE
sequence D
description Substrate binding => ECO:0000250
source Swiss-Prot : SWS_FT_FI3

11) chain A
residue 4
type SITE
sequence I
description Interaction with RANBP2 => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

12) chain A
residue 25
type SITE
sequence V
description Interaction with RANBP2 => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

13) chain A
residue 57
type SITE
sequence L
description Interaction with RANBP2 => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

14) chain A
residue 65
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P63279
source Swiss-Prot : SWS_FT_FI5


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