eF-site ID 2uv3-AB PDB Code 2uv3 Chain A, B click to enlarge Title Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. Classification RECEPTOR Compound TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 Source (2UV3) Sequence A:  EELQVIQPDKSVSVAAGESAILHCTVTSLIPVGPIQWFRG AGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNI TPADAGTYYCVKFRKGSPDTEFKSGAGTELSVRAKPSTRH B:  EELQVIQPDKSVSVAAGESAILHCTVTSLIPVGPIQWFRG AGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNI TPADAGTYYCVKFRKGSPDTEFKSGAGTELSVRAKPSTRH HH Description (1)  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 Functional site 1) chain A residue 29 type sequence S description BINDING SITE FOR RESIDUE MES B1124 source : AC1 2) chain A residue 30 type sequence L description BINDING SITE FOR RESIDUE MES B1124 source : AC1 3) chain A residue 31 type sequence I description BINDING SITE FOR RESIDUE MES B1124 source : AC1 4) chain B residue 10 type sequence D description BINDING SITE FOR RESIDUE MES B1124 source : AC1 5) chain B residue 24 type sequence H description BINDING SITE FOR RESIDUE MES B1124 source : AC1 6) chain A residue 10 type sequence D description BINDING SITE FOR RESIDUE MES A1122 source : AC2 7) chain A residue 13 type sequence V description BINDING SITE FOR RESIDUE MES A1122 source : AC2 8) chain A residue 24 type sequence H description BINDING SITE FOR RESIDUE MES A1122 source : AC2 9) chain B residue 29 type sequence S description BINDING SITE FOR RESIDUE MES A1122 source : AC2 10) chain B residue 30 type sequence L description BINDING SITE FOR RESIDUE MES A1122 source : AC2 11) chain A residue 66 type sequence S description BINDING SITE FOR RESIDUE SO4 A1123 source : AC3 12) chain A residue 67 type sequence T description BINDING SITE FOR RESIDUE SO4 A1123 source : AC3 13) chain B residue 80 type sequence N description BINDING SITE FOR RESIDUE SO4 A1123 source : AC3 14) chain B residue 82 type sequence T description BINDING SITE FOR RESIDUE SO4 A1123 source : AC3 15) chain A residue 69 type sequence R description BINDING SITE FOR RESIDUE SO4 A1124 source : AC4 16) chain B residue 9 type sequence P description BINDING SITE FOR RESIDUE SO4 B1125 source : AC5 17) chain B residue 10 type sequence D description BINDING SITE FOR RESIDUE SO4 B1125 source : AC5 18) chain B residue 11 type sequence K description BINDING SITE FOR RESIDUE SO4 B1125 source : AC5 19) chain B residue 12 type sequence S description BINDING SITE FOR RESIDUE SO4 B1125 source : AC5 20) chain A residue 69 type sequence R description BINDING SITE FOR RESIDUE SO4 A1125 source : AC6 21) chain A residue 9 type sequence P description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 22) chain A residue 10 type sequence D description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 23) chain A residue 11 type sequence K description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 24) chain A residue 12 type sequence S description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 25) chain B residue 2 type sequence E description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 26) chain A residue 59 type sequence R description BINDING SITE FOR RESIDUE SO4 A1127 source : AC8 27) chain A residue 79 type sequence S description BINDING SITE FOR RESIDUE SO4 A1127 source : AC8 28) chain A residue 80 type sequence N description BINDING SITE FOR RESIDUE SO4 A1127 source : AC8

Display surface Download Links