eF-site ID 2uv3-A PDB Code 2uv3 Chain A click to enlarge Title Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. Classification RECEPTOR Compound TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 Source (2UV3) Sequence A:  EELQVIQPDKSVSVAAGESAILHCTVTSLIPVGPIQWFRG AGPARELIYNQKEGHFPRVTTVSESTKRENMDFSISISNI TPADAGTYYCVKFRKGSPDTEFKSGAGTELSVRAKPSTRH Description (1)  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 Functional site 1) chain A residue 29 type sequence S description BINDING SITE FOR RESIDUE MES B1124 source : AC1 2) chain A residue 30 type sequence L description BINDING SITE FOR RESIDUE MES B1124 source : AC1 3) chain A residue 31 type sequence I description BINDING SITE FOR RESIDUE MES B1124 source : AC1 4) chain A residue 10 type sequence D description BINDING SITE FOR RESIDUE MES A1122 source : AC2 5) chain A residue 13 type sequence V description BINDING SITE FOR RESIDUE MES A1122 source : AC2 6) chain A residue 24 type sequence H description BINDING SITE FOR RESIDUE MES A1122 source : AC2 7) chain A residue 66 type sequence S description BINDING SITE FOR RESIDUE SO4 A1123 source : AC3 8) chain A residue 67 type sequence T description BINDING SITE FOR RESIDUE SO4 A1123 source : AC3 9) chain A residue 69 type sequence R description BINDING SITE FOR RESIDUE SO4 A1124 source : AC4 10) chain A residue 69 type sequence R description BINDING SITE FOR RESIDUE SO4 A1125 source : AC6 11) chain A residue 9 type sequence P description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 12) chain A residue 10 type sequence D description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 13) chain A residue 11 type sequence K description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 14) chain A residue 12 type sequence S description BINDING SITE FOR RESIDUE SO4 A1126 source : AC7 15) chain A residue 59 type sequence R description BINDING SITE FOR RESIDUE SO4 A1127 source : AC8 16) chain A residue 79 type sequence S description BINDING SITE FOR RESIDUE SO4 A1127 source : AC8 17) chain A residue 80 type sequence N description BINDING SITE FOR RESIDUE SO4 A1127 source : AC8

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