eF-site ID 2uue-B PDB Code 2uue Chain B click to enlarge Title REPLACE: A strategy for Iterative Design of Cyclin Binding Groove Inhibitors Classification TRANSFERASE/INHIBITOR Compound CELL DIVISION PROTEIN KINASE 2 Source (2UUE) Sequence B:  VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQ LVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRM EHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYK NSKYHGVSLLNPPETLNL Description Functional site 1) chain B residue 217 type sequence W description BINDING SITE FOR RESIDUE GVC E 1433 source : AC3 2) chain B residue 220 type sequence E description BINDING SITE FOR RESIDUE GVC E 1433 source : AC3 3) chain B residue 221 type sequence V description BINDING SITE FOR RESIDUE GVC E 1433 source : AC3 4) chain B residue 254 type sequence Q description BINDING SITE FOR RESIDUE GVC E 1433 source : AC3 5) chain B residue 281 type sequence I description BINDING SITE FOR RESIDUE GVC E 1433 source : AC3 6) chain B residue 283 type sequence D description BINDING SITE FOR RESIDUE GVC E 1433 source : AC3 7) chain B residue 211-242 type prosite sequence RAILVDWLVEVGEEYKLQNETLHLAVNYIDRF description CYCLINS Cyclins signature. RaiLvdWLvevgeeykLqnetLhlAVnYIDRF source prosite : PS00292

Display surface Download Links