eF-site ID 2rjf-ABCDE
PDB Code 2rjf
Chain A, B, C, D, E

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Title Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 12-30), orthorhombic form I
Classification TRANSCRIPTION
Compound Lethal(3)malignant brain tumor-like protein
Source null (2RJF)
Sequence A:  WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLE
GIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNA
NSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRA
QAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVA
SVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQK
QGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRP
PHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDG
WSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGP
B:  RHRXVLRDNI
C:  WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLE
GIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNA
NSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRA
QAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVA
SVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQK
QGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRP
PHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDG
WSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGP
D:  RHRXVLRDN
E:  WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLE
GIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNA
NSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRA
QAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVA
SVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQK
QGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRP
PHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDG
WSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGP
Description


Functional site

1) chain A
residue 423
type SITE
sequence C
description Mediates recognition of monomethylated and dimethylated peptides
source Swiss-Prot : SWS_FT_FI1

2) chain C
residue 423
type SITE
sequence C
description Mediates recognition of monomethylated and dimethylated peptides
source Swiss-Prot : SWS_FT_FI1

3) chain E
residue 423
type SITE
sequence C
description Mediates recognition of monomethylated and dimethylated peptides
source Swiss-Prot : SWS_FT_FI1

4) chain A
residue 426
type SITE
sequence K
description Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides
source Swiss-Prot : SWS_FT_FI2

5) chain C
residue 426
type SITE
sequence K
description Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides
source Swiss-Prot : SWS_FT_FI2

6) chain E
residue 426
type SITE
sequence K
description Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides
source Swiss-Prot : SWS_FT_FI2


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