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eF-site ID
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2rjf-A |
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PDB Code
|
2rjf |
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Chain
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A |
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click to enlarge
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Title
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Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 12-30), orthorhombic form I |
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Classification
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TRANSCRIPTION |
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Compound
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Lethal(3)malignant brain tumor-like protein |
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Source
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Homo sapiens (Human) (2RJF) |
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Sequence
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A: |
WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLE
GIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNA
NSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRA
QAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVA
SVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQK
QGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRP
PHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDG
WSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGP
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Description
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Functional site
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1)
|
chain |
A |
| residue |
423 |
| type |
SITE |
| sequence |
C
|
| description |
Mediates recognition of monomethylated and dimethylated peptides
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
|
chain |
A |
| residue |
426 |
| type |
SITE |
| sequence |
K
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| description |
Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides
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| source |
Swiss-Prot : SWS_FT_FI2
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