eF-site ID 2rjc-C PDB Code 2rjc Chain C click to enlarge Title Crystal structure of L3MBTL1 protein in complex with MES Classification TRANSCRIPTION Compound Lethal(3)malignant brain tumor-like protein Source Homo sapiens (Human) (LMBTL_HUMAN) Sequence C:  WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLE GIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNA NSPDIHPAGWFEKTGHKLQPPKGYEFSWSQYLRSTRAQAA PKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVT DVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGK PLTPPQDYFCWEKYLEETGASAVPTWAFKVRPPHSFLVNM KLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFW IDADHPDIHPAGWCSKTGHPLQPPLG Description Functional site 1) chain C residue 461 type sequence R description BINDING SITE FOR RESIDUE SO4 B 611 source : AC4 2) chain C residue 482 type sequence H description BINDING SITE FOR RESIDUE SO4 C 610 source : AC5 3) chain C residue 484 type sequence D description BINDING SITE FOR RESIDUE SO4 C 610 source : AC5 4) chain C residue 485 type sequence G description BINDING SITE FOR RESIDUE SO4 C 610 source : AC5 5) chain C residue 487 type sequence S description BINDING SITE FOR RESIDUE MES A 601 source : AC6 6) chain C residue 488 type sequence H description BINDING SITE FOR RESIDUE MES A 601 source : AC6 7) chain C residue 489 type sequence G description BINDING SITE FOR RESIDUE MES A 601 source : AC6 8) chain C residue 248 type sequence D description BINDING SITE FOR RESIDUE MES C 603 source : AC9 9) chain C residue 250 type sequence Q description BINDING SITE FOR RESIDUE MES C 603 source : AC9 10) chain C residue 256 type sequence F description BINDING SITE FOR RESIDUE MES C 603 source : AC9 11) chain C residue 272 type sequence F description BINDING SITE FOR RESIDUE MES C 603 source : AC9 12) chain C residue 275 type sequence Y description BINDING SITE FOR RESIDUE MES C 603 source : AC9 13) chain C residue 279 type sequence H description BINDING SITE FOR RESIDUE MES C 603 source : AC9 14) chain C residue 459 type sequence D description BINDING SITE FOR RESIDUE MES C 605 source : BC1 15) chain C residue 461 type sequence R description BINDING SITE FOR RESIDUE MES C 605 source : BC1 16) chain C residue 462 type sequence N description BINDING SITE FOR RESIDUE MES C 605 source : BC1 17) chain C residue 467 type sequence R description BINDING SITE FOR RESIDUE MES C 605 source : BC1 18) chain C residue 483 type sequence F description BINDING SITE FOR RESIDUE MES C 605 source : BC1 19) chain C residue 486 type sequence W description BINDING SITE FOR RESIDUE MES C 605 source : BC1 20) chain C residue 490 type sequence Y description BINDING SITE FOR RESIDUE MES C 605 source : BC1 21) chain C residue 206 type sequence W description BINDING SITE FOR RESIDUE MES C 606 source : BC2 22) chain C residue 207 type sequence S description BINDING SITE FOR RESIDUE MES C 606 source : BC2 23) chain C residue 210 type sequence S description BINDING SITE FOR RESIDUE MES C 606 source : BC2 24) chain C residue 211 type sequence Y description BINDING SITE FOR RESIDUE MES C 606 source : BC2 25) chain C residue 214 type sequence E description BINDING SITE FOR RESIDUE MES C 606 source : BC2 26) chain C residue 423 type SITE sequence C description Mediates recognition of monomethylated and dimethylated peptides source Swiss-Prot : SWS_FT_FI1 27) chain C residue 426 type SITE sequence K description Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides source Swiss-Prot : SWS_FT_FI2

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