eF-site ID 2rjc-A PDB Code 2rjc Chain A click to enlarge Title Crystal structure of L3MBTL1 protein in complex with MES Classification TRANSCRIPTION Compound Lethal(3)malignant brain tumor-like protein Source Homo sapiens (Human) (LMBTL_HUMAN) Sequence A:  WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLE GIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNA NSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRA QAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVA SVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQK QGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRP PHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDG WSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPL Description Functional site 1) chain A residue 275 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 607 source : AC1 2) chain A residue 276 type sequence S description BINDING SITE FOR RESIDUE SO4 A 607 source : AC1 3) chain A residue 279 type sequence H description BINDING SITE FOR RESIDUE SO4 A 607 source : AC1 4) chain A residue 307 type sequence K description BINDING SITE FOR RESIDUE SO4 A 607 source : AC1 5) chain A residue 482 type sequence H description BINDING SITE FOR RESIDUE SO4 A 609 source : AC2 6) chain A residue 484 type sequence D description BINDING SITE FOR RESIDUE SO4 A 609 source : AC2 7) chain A residue 485 type sequence G description BINDING SITE FOR RESIDUE SO4 A 609 source : AC2 8) chain A residue 355 type sequence D description BINDING SITE FOR RESIDUE MES A 601 source : AC6 9) chain A residue 358 type sequence N description BINDING SITE FOR RESIDUE MES A 601 source : AC6 10) chain A residue 361 type sequence L description BINDING SITE FOR RESIDUE MES A 601 source : AC6 11) chain A residue 363 type sequence C description BINDING SITE FOR RESIDUE MES A 601 source : AC6 12) chain A residue 379 type sequence F description BINDING SITE FOR RESIDUE MES A 601 source : AC6 13) chain A residue 382 type sequence W description BINDING SITE FOR RESIDUE MES A 601 source : AC6 14) chain A residue 386 type sequence Y description BINDING SITE FOR RESIDUE MES A 601 source : AC6 15) chain A residue 459 type sequence D description BINDING SITE FOR RESIDUE MES A 602 source : AC7 16) chain A residue 461 type sequence R description BINDING SITE FOR RESIDUE MES A 602 source : AC7 17) chain A residue 462 type sequence N description BINDING SITE FOR RESIDUE MES A 602 source : AC7 18) chain A residue 467 type sequence R description BINDING SITE FOR RESIDUE MES A 602 source : AC7 19) chain A residue 483 type sequence F description BINDING SITE FOR RESIDUE MES A 602 source : AC7 20) chain A residue 486 type sequence W description BINDING SITE FOR RESIDUE MES A 602 source : AC7 21) chain A residue 490 type sequence Y description BINDING SITE FOR RESIDUE MES A 602 source : AC7 22) chain A residue 423 type SITE sequence C description Mediates recognition of monomethylated and dimethylated peptides source Swiss-Prot : SWS_FT_FI1 23) chain A residue 426 type SITE sequence K description Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides source Swiss-Prot : SWS_FT_FI2

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