eF-site ID 2rb4-AB PDB Code 2rb4 Chain A, B click to enlarge Title Crystal structure of the Helicase domain of human DDX25 RNA helicase Classification HYDROLASE Compound ATP-dependent RNA helicase DDX25 Source Homo sapiens (Human) (DDX25_HUMAN) Sequence A:  LTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQ TRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRD GKEKVLITTNVCARGIDVKQVTIVVNFDLPVGEEPDYETY LHRIGRTKKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNA EDMD B:  LTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQ TRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRD GKEKVLITTNVCARGIDVKQVTIVVNFDLPVGEEPDYETY LHRIGRTKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAE DMD Description Functional site 1) chain A residue 400 type sequence R description BINDING SITE FOR RESIDUE CL A 1 source : AC1 2) chain A residue 348 type sequence R description BINDING SITE FOR RESIDUE CL A 2 source : AC2 3) chain A residue 307 type sequence L description BINDING SITE FOR RESIDUE SO4 B 1 source : AC3 4) chain B residue 382 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 1 source : AC3 5) chain B residue 385 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1 source : AC3 6) chain A residue 382 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 480 source : AC4 7) chain A residue 385 type sequence R description BINDING SITE FOR RESIDUE SO4 A 480 source : AC4 8) chain A residue 398 type sequence C description BINDING SITE FOR RESIDUE ZN A 481 source : AC5 9) chain A residue 430 type sequence H description BINDING SITE FOR RESIDUE ZN A 481 source : AC5 10) chain B residue 398 type sequence C description BINDING SITE FOR RESIDUE ZN A 481 source : AC5 11) chain B residue 400 type sequence R description BINDING SITE FOR RESIDUE ZN A 481 source : AC5 12) chain B residue 430 type sequence H description BINDING SITE FOR RESIDUE ZN A 481 source : AC5

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