eF-site ID 2r7z-B PDB Code 2r7z Chain B click to enlarge Title Cisplatin lesion containing RNA polymerase II elongation complex Classification TRANSCRIPTION/DNA-RNA HYBRID Compound 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3' Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence B:  DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL QDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEAR LRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATES DLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFK KAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSAR TIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVND WQMLEMLKPCVEDGFVIQDRETALDFIGKEKRIQYAKDIL QKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQD DRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTV ELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLN RYTYSSTLSHLRRTNTPIKLAKPRQLHNTHWGLVCPAETP EGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLED YVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGD INPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGH KELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEE EESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEI HPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLT NYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNA IVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQE KKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGV RVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLVTT NQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRR EDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAA LSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGH TGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTR QPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASD AFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHI PYAAKLLFQELMAMNITPRLYTDRSRDF Description (1)  DNA-DIRECTED RNA POLYMERASE II (E.C.2.7.7.6)/DNA-DIRECTED RNA POLYMERASES POLYPEPTIDES/RNA Functional site 1) chain B residue 1163 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC4 2) chain B residue 1166 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC4 3) chain B residue 1182 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC4 4) chain B residue 1185 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC4 5) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1 6) chain B residue 1185 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI2 7) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166 8) chain B residue 919 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI3

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