eF-site ID 2r7g-A PDB Code 2r7g Chain A click to enlarge Title Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain Classification TRANSCRIPTION REPRESSOR, CELL CYCLE Compound Retinoblastoma-associated protein Source null (E1A_ADE05) Sequence A:  NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRV KDIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMES MLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYS RSTGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTRE MIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDKSTSLSL FYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQ NEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYK DLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNIL QYASTRPPTLSPIPHI Description Functional site 1) chain A residue 406 type sequence N description BINDING SITE FOR RESIDUE SO4 A 902 source : AC1 2) chain A residue 407 type sequence C description BINDING SITE FOR RESIDUE SO4 A 902 source : AC1 3) chain A residue 408 type sequence T description BINDING SITE FOR RESIDUE SO4 A 902 source : AC1 4) chain A residue 472 type sequence N description BINDING SITE FOR RESIDUE SO4 A 902 source : AC1 5) chain A residue 473 type sequence F description BINDING SITE FOR RESIDUE SO4 A 902 source : AC1 6) chain A residue 474 type sequence S description BINDING SITE FOR RESIDUE SO4 A 902 source : AC1 7) chain A residue 574 type sequence K description BINDING SITE FOR RESIDUE SO4 C 901 source : AC2 8) chain A residue 685 type MOD_RES sequence Q description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI4 9) chain A residue 567 type MOD_RES sequence S description Phosphoserine; by CDK2 => ECO:0000269|PubMed:10499802 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 669 type MOD_RES sequence L description Phosphoserine => ECO:0000250|UniProtKB:P13405 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 673 type MOD_RES sequence H description Phosphoserine; by CHEK2 and CHEK1 => ECO:0000269|PubMed:17380128, ECO:0007744|PubMed:18669648 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links