|
|
eF-site ID
|
2q6g-B |
|
PDB Code
|
2q6g |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal structure of SARS-CoV main protease H41A mutant in complex with an N-terminal substrate |
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Classification
|
HYDROLASE |
|
Compound
|
severe acute respiratory syndrome coronavirus (SARS-CoV) |
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Source
|
null (2Q6G) |
|
|
Sequence
|
B: |
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPR
AVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGH
SMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG
SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTI
TLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRT
ILGSTILEDEFTPFDVVRQCSG
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
41 |
| type |
SITE |
| sequence |
A
|
| description |
Cleavage; by 3CL-PRO => ECO:0000269|PubMed:14561748
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
145 |
| type |
SITE |
| sequence |
C
|
| description |
Cleavage; by 3CL-PRO => ECO:0000269|PubMed:14561748
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
145 |
| type |
catalytic |
| sequence |
C
|
| description |
830
|
| source |
MCSA : MCSA2
|
|
|
4)
|
chain |
B |
| residue |
41 |
| type |
catalytic |
| sequence |
A
|
| description |
830
|
| source |
MCSA : MCSA2
|
|
|
5)
|
chain |
B |
| residue |
143 |
| type |
catalytic |
| sequence |
G
|
| description |
830
|
| source |
MCSA : MCSA2
|
|
|
|