eF-site ID 2q6f-A PDB Code 2q6f Chain A click to enlarge Title Crystal structure of infectious bronchitis virus (IBV) main protease in complex with a Michael acceptor inhibitor N3 Classification HYDROLASE Compound Infectious bronchitis virus (IBV) main protease Source Infectious bronchitis virus (2Q6F) Sequence A:  SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPR HVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRL KGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYM HHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTN NIVAWLYAAIISVPKWLESTTVSIEDYNRWASDNGFTPFS TSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYN FEDELTPESVFNQV Description Functional site 1) chain A residue 41 type sequence H description BINDING SITE FOR CHAIN D source : AC1 2) chain A residue 138 type sequence F description BINDING SITE FOR CHAIN D source : AC1 3) chain A residue 140 type sequence A description BINDING SITE FOR CHAIN D source : AC1 4) chain A residue 141 type sequence G description BINDING SITE FOR CHAIN D source : AC1 5) chain A residue 143 type sequence C description BINDING SITE FOR CHAIN D source : AC1 6) chain A residue 161 type sequence H description BINDING SITE FOR CHAIN D source : AC1 7) chain A residue 162 type sequence H description BINDING SITE FOR CHAIN D source : AC1 8) chain A residue 163 type sequence L description BINDING SITE FOR CHAIN D source : AC1 9) chain A residue 164 type sequence E description BINDING SITE FOR CHAIN D source : AC1 10) chain A residue 170 type sequence H description BINDING SITE FOR CHAIN D source : AC1 11) chain A residue 186 type sequence E description BINDING SITE FOR CHAIN D source : AC1 12) chain A residue 187 type sequence E description BINDING SITE FOR CHAIN D source : AC1 13) chain A residue 188 type sequence V description BINDING SITE FOR CHAIN D source : AC1 14) chain A residue 189 type sequence A description BINDING SITE FOR CHAIN D source : AC1 15) chain A residue 256 type sequence S description BINDING SITE FOR CHAIN D source : AC1 16) chain A residue 260 type sequence G description BINDING SITE FOR CHAIN D source : AC1 17) chain A residue 41 type ACT_SITE sequence H description For 3CL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00772 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 143 type ACT_SITE sequence C description For 3CL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00772 source Swiss-Prot : SWS_FT_FI1

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