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eF-site ID
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2px7-B |
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PDB Code
|
2px7 |
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Chain
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B |
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click to enlarge
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Title
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Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8 |
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Classification
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TRANSFERASE |
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Compound
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2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
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Source
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Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) (ISPD_THET8) |
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Sequence
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B: |
MEVSVLIPAAGPKAFLQVGGRTLLEWTLAAFRDAAEVLVA
LPPGAEPPKGLGAVFLEGGATRQASVARLLEAASLPLVLV
HDVARPFVSRGLVARVLEAAQRSGAAVPVLPVPDTLMAPE
GEAYGRVVPREAFRLVQTPQGFFTALLREAHAYARRKGLE
ASDDAQLVQALGYPVALVEGEATAFKITHPQDLVLAEALA
RV
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Description
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Functional site
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|
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1)
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chain |
B |
| residue |
21 |
| type |
SITE |
| sequence |
K
|
| description |
Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00108
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
B |
| residue |
138 |
| type |
SITE |
| sequence |
R
|
| description |
Positions MEP for the nucleophilic attack => ECO:0000255|HAMAP-Rule:MF_00108
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
B |
| residue |
194 |
| type |
SITE |
| sequence |
K
|
| description |
Positions MEP for the nucleophilic attack => ECO:0000255|HAMAP-Rule:MF_00108
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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