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|
eF-site ID
|
2pq5-ABCD |
|
PDB Code
|
2pq5 |
|
Chain
|
A, B, C, D |
|
click to enlarge
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Title
|
Crystal structure of Dual specificity protein phosphatase 13 (DUSP13) |
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Classification
|
HYDROLASE |
|
Compound
|
Dual specificity protein phosphatase 13 |
|
Source
|
null (DUS13_HUMAN) |
|
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Sequence
|
A: |
PPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDK
SKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEA
DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSR
SATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQL
QVLDNRLGR
|
| B: |
PPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDK
SKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEA
DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSR
SATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQL
QVLDNRLG
|
| C: |
QPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARD
KSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIE
ADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVS
RSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQ
LQVLDNRLG
|
| D: |
PPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDK
SKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEA
DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSR
SATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQL
QVLDNRLGR
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
138 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
138 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
C |
| residue |
138 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
D |
| residue |
138 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
136-146 |
| type |
prosite |
| sequence |
VHCAMGVSRSA
|
| description |
TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCamGvsRSA
|
| source |
prosite : PS00383
|
|
|
|