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eF-site ID
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2poq-X |
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PDB Code
|
2poq |
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Chain
|
X |
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click to enlarge
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Title
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Dimeric Dihydrodiol Dehydrogenase complexed with inhibitor, Isoascorbic acid |
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Classification
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OXIDOREDUCTASE |
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Compound
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Dimeric dihydrodiol dehydrogenase |
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Source
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Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (Q9TQS6_MACFA) |
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Sequence
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X: |
ALRWGIVSVGLISSDFTAVLQTLPRSEHQVVAVAARDLSR
AKEFAQKHDIPKAYGSYEELAKDPNVEVAYVGTQHPQHKA
AVMLCLAAGKAVLCEKPMGVNAAEVREMVTEARSRGLFLM
EAIWTRFFPASEALRSVLAQGTLGDLRVARAEFGKNLTHV
PRAVDWAQAGGALLDLGIYCVQFISMVFGGQKPEKISVMG
RRHETGVDDTVTVLLQYPGEVHGSFTCSITAQLSNTASVS
GTKGMAQLLNPCWCPTELVVKGEHKEFLLPPVPKNCNFDN
GAGMSYEAKHVRECLRKGLKESPVIPLVESELLADILEEV
RRAIGVTFPQD
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Description
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Functional site
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|
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1)
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chain |
X |
| residue |
1071 |
| type |
SITE |
| sequence |
Y
|
| description |
May play an important role in coenzyme binding => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
X |
| residue |
1079 |
| type |
SITE |
| sequence |
H
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| description |
May play an important role in coenzyme binding => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
X |
| residue |
1097 |
| type |
SITE |
| sequence |
K
|
| description |
May play an important role in coenzyme binding => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
|
chain |
X |
| residue |
1176 |
| type |
SITE |
| sequence |
D
|
| description |
May play an important role for the adaptation of the alcohol substrate into the binding site => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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5)
|
chain |
X |
| residue |
1180 |
| type |
SITE |
| sequence |
Y
|
| description |
May play an important role in catalytic activity => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI3
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