eF-site ID 2pob-B PDB Code 2pob Chain B click to enlarge Title PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709 Classification GENE REGULATION Compound Peroxisome proliferator-activated receptor gamma Source null (PPARG_HUMAN) Sequence B:  PESADLRALAKHLYDSYIKSFPLTKAKARAILTGSPFVIY DMNSLMMGQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIP GFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEG QGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLN HPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETLHP LLQEIYK Description Functional site 1) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE GOL B 478 source : AC2 2) chain B residue 341 type sequence I description BINDING SITE FOR RESIDUE GOL B 478 source : AC2 3) chain B residue 342 type sequence S description BINDING SITE FOR RESIDUE GOL B 478 source : AC2 4) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2 5) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 6) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 7) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 8) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1

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