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eF-site ID
|
2pgi-A |
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PDB Code
|
2pgi |
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Chain
|
A |
|
click to enlarge
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Title
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THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE-AN ENZYME WITH AUTOCRINE MOTILITY FACTOR ACTIVITY IN TUMOR CELLS |
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Classification
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ISOMERASE |
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Compound
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PHOSPHOGLUCOSE ISOMERASE |
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Source
|
Geobacillus stearothermophilus (Bacillus stearothermophilus) (G6PIB_BACST) |
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Sequence
|
A: |
AISFDYSNALPFMQENELDYLSEFVKAAHHMLHERKGPGS
DFLGWVDWPIRYDKNEFSRIKQAAERIRNHSDALVVIGIG
GSYLGARAAIEALSHTFHNQMNDTTQIYFAGQNISSTYIS
HLLDVLEGKDLSINVISKSGTTTEPAIAFRIFRDYMEKKY
GKEEARKRIYVTTDRTKGALKKLADQEGYETFVIPDNIGG
RYSVLTAVGLLPIAVAGLNIDRMMEGAASAYHKYNNPDLL
TNESYQYAAVRNILYRKGKAIELLVNYEPSLHYVSEWWKQ
LFGESEGKDQKGLFPASVDFTTDLHSMGQYVQEGRRNLIE
TVLHVKKPQIELTIQEDPENIDGLNFLAGKTLDEVNKKAF
QGTLLAHVDGGVPNLIVELDEMNEYTFGEMVYFFEKACGI
SGHLLGVNPFDQPGVEAYKKNMFALLGKPGFEDEKAALMK
RL
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Description
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Functional site
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|
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1)
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chain |
A |
| residue |
285 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton donor => ECO:0000255|HAMAP-Rule:MF_00473
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
306 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00473
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
420 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00473
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
A |
| residue |
403-420 |
| type |
prosite |
| sequence |
GHLLGVNPFDQPGVEAYK
|
| description |
P_GLUCOSE_ISOMERASE_2 Phosphoglucose isomerase signature 2. GhLLgvnpFDQpGVEayK
|
| source |
prosite : PS00174
|
|
|
5)
|
chain |
A |
| residue |
197-210 |
| type |
prosite |
| sequence |
DNIGGRYSVLTAVG
|
| description |
P_GLUCOSE_ISOMERASE_1 Phosphoglucose isomerase signature 1. DnIGGRYSVlTAVG
|
| source |
prosite : PS00765
|
|
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