eF-site ID 2p5u-ABCD PDB Code 2p5u Chain A, B, C, D click to enlarge Title Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD Classification ISOMERASE Compound UDP-glucose 4-epimerase Source null (Q5SKQ2_THET8) Sequence A:  MRVLVTGGAGFIGSHIVEDLLARGLEVAVLDNLATGKREN VPKGVPFFRVDLRDKEGVERAFREFRPTHVSHQAAQASVK VSVEDPVLDFEVNLLGGLNLLEACRQYGVEKLVFASTGGA IYGEVPEGERAEETWPPRPKSPYAASKAAFEHYLSVYGQS YGLKWVSLRYGNVYGPRQDPHGEAGVVAIFAERVLKGLPV TLYARKTPGDEGCVRDYVYVGDVAEAHALALFSLEGIYNV GTGEGHTTREVLMAVAEAAGKAPEVQPAPPRPGDLERSVL SPLKLMAHGWRPKVGFQEGIRLTVDHFRGAV B:  MRVLVTGGAGFIGSHIVEDLLARGLEVAVLDNLATGKREN VPKGVPFFRVDLRDKEGVERAFREFRPTHVSHQAAQASVK VSVEDPVLDFEVNLLGGLNLLEACRQYGVEKLVFASTGGA IYGEVPEGERAEETWPPRPKSPYAASKAAFEHYLSVYGQS YGLKWVSLRYGNVYGPRQDPHGEAGVVAIFAERVLKGLPV TLYARKTPGDEGCVRDYVYVGDVAEAHALALFSLEGIYNV GTGEGHTTREVLMAVAEAAGKAPEVQPAPPRPGDLERSVL SPLKLMAHGWRPKVGFQEGIRLTVDHFRGAV C:  MRVLVTGGAGFIGSHIVEDLLARGLEVAVLDNLATGKREN VPKGVPFFRVDLRDKEGVERAFREFRPTHVSHQAAQASVK VSVEDPVLDFEVNLLGGLNLLEACRQYGVEKLVFASTGGA IYGEVPEGERAEETWPPRPKSPYAASKAAFEHYLSVYGQS YGLKWVSLRYGNVYGPRQDPHGEAGVVAIFAERVLKGLPV TLYARKTPGDEGCVRDYVYVGDVAEAHALALFSLEGIYNV GTGEGHTTREVLMAVAEAAGKAPEVQPAPPRPGDLERSVL SPLKLMAHGWRPKVGFQEGIRLTVDHFRGAV D:  MRVLVTGGAGFIGSHIVEDLLARGLEVAVLDNLATGKREN VPKGVPFFRVDLRDKEGVERAFREFRPTHVSHQAAQASVK VSVEDPVLDFEVNLLGGLNLLEACRQYGVEKLVFASTGGA IYGEVPEGERAEETWPPRPKSPYAASKAAFEHYLSVYGQS YGLKWVSLRYGNVYGPRQDPHGEAGVVAIFAERVLKGLPV TLYARKTPGDEGCVRDYVYVGDVAEAHALALFSLEGIYNV GTGEGHTTREVLMAVAEAAGKAPEVQPAPPRPGDLERSVL SPLKLMAHGWRPKVGFQEGIRLTVDHFRGAV Description Functional site 1) chain A residue 7 type sequence G description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 2) chain A residue 9 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 3) chain A residue 10 type sequence G description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 4) chain A residue 11 type sequence F description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 5) chain A residue 12 type sequence I description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 6) chain A residue 31 type sequence D description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 7) chain A residue 32 type sequence N description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 8) chain A residue 33 type sequence L description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 9) chain A residue 34 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 10) chain A residue 35 type sequence T description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 11) chain A residue 36 type sequence G description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 12) chain A residue 50 type sequence V description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 13) chain A residue 51 type sequence D description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 14) chain A residue 52 type sequence L description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 15) chain A residue 73 type sequence Q description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 16) chain A residue 74 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 17) chain A residue 75 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 18) chain A residue 77 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 19) chain A residue 115 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 20) chain A residue 116 type sequence S description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 21) chain A residue 143 type sequence Y description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 22) chain A residue 147 type sequence K description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 23) chain A residue 170 type sequence Y description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 24) chain A residue 171 type sequence G description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 25) chain A residue 173 type sequence V description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 26) chain A residue 184 type sequence A description BINDING SITE FOR RESIDUE NAD A 1118 source : AC1 27) chain B residue 7 type sequence G description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 28) chain B residue 9 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 29) chain B residue 10 type sequence G description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 30) chain B residue 11 type sequence F description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 31) chain B residue 12 type sequence I description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 32) chain B residue 31 type sequence D description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 33) chain B residue 32 type sequence N description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 34) chain B residue 33 type sequence L description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 35) chain B residue 34 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 36) chain B residue 35 type sequence T description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 37) chain B residue 36 type sequence G description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 38) chain B residue 50 type sequence V description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 39) chain B residue 51 type sequence D description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 40) chain B residue 52 type sequence L description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 41) chain B residue 73 type sequence Q description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 42) chain B residue 74 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 43) chain B residue 75 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 44) chain B residue 77 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 45) chain B residue 92 type sequence V description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 46) chain B residue 115 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 47) chain B residue 116 type sequence S description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 48) chain B residue 143 type sequence Y description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 49) chain B residue 147 type sequence K description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 50) chain B residue 171 type sequence G description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 51) chain B residue 173 type sequence V description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 52) chain B residue 183 type sequence E description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 53) chain B residue 184 type sequence A description BINDING SITE FOR RESIDUE NAD B 1118 source : AC2 54) chain C residue 6 type sequence T description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 55) chain C residue 9 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 56) chain C residue 10 type sequence G description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 57) chain C residue 11 type sequence F description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 58) chain C residue 12 type sequence I description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 59) chain C residue 31 type sequence D description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 60) chain C residue 32 type sequence N description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 61) chain C residue 33 type sequence L description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 62) chain C residue 34 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 63) chain C residue 35 type sequence T description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 64) chain C residue 36 type sequence G description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 65) chain C residue 50 type sequence V description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 66) chain C residue 51 type sequence D description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 67) chain C residue 52 type sequence L description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 68) chain C residue 73 type sequence Q description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 69) chain C residue 74 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 70) chain C residue 75 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 71) chain C residue 77 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 72) chain C residue 92 type sequence V description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 73) chain C residue 115 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 74) chain C residue 116 type sequence S description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 75) chain C residue 143 type sequence Y description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 76) chain C residue 147 type sequence K description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 77) chain C residue 171 type sequence G description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 78) chain C residue 173 type sequence V description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 79) chain C residue 183 type sequence E description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 80) chain C residue 184 type sequence A description BINDING SITE FOR RESIDUE NAD C 1118 source : AC3 81) chain D residue 7 type sequence G description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 82) chain D residue 9 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 83) chain D residue 10 type sequence G description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 84) chain D residue 11 type sequence F description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 85) chain D residue 12 type sequence I description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 86) chain D residue 31 type sequence D description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 87) chain D residue 32 type sequence N description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 88) chain D residue 33 type sequence L description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 89) chain D residue 34 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 90) chain D residue 35 type sequence T description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 91) chain D residue 36 type sequence G description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 92) chain D residue 50 type sequence V description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 93) chain D residue 51 type sequence D description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 94) chain D residue 52 type sequence L description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 95) chain D residue 73 type sequence Q description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 96) chain D residue 74 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 97) chain D residue 75 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 98) chain D residue 77 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 99) chain D residue 92 type sequence V description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 100) chain D residue 115 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 101) chain D residue 116 type sequence S description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 102) chain D residue 143 type sequence Y description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 103) chain D residue 147 type sequence K description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 104) chain D residue 170 type sequence Y description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 105) chain D residue 171 type sequence G description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 106) chain D residue 173 type sequence V description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 107) chain D residue 179 type sequence D description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 108) chain D residue 183 type sequence E description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4 109) chain D residue 184 type sequence A description BINDING SITE FOR RESIDUE NAD D 1118 source : AC4

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