eF-site ID 2p0a-A PDB Code 2p0a Chain A click to enlarge Title The crystal structure of human synapsin III (SYN3) in complex with AMPPNP Classification NEUROPEPTIDE Compound Synapsin-3 Source Homo sapiens (Human) (SYN3_HUMAN) Sequence A:  RPRILLVIDDAHTDWSKYFHGKKVNGEIEIRVEQAEFSEL NLAAYVTGGCMVDMQRSFKPDFILVRQHAYSMALGEDYRS LVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLG PEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKI KVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIG SNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSC SEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVE EDRQLMADLVVSKMSQLP Description Functional site 1) chain A residue 170 type sequence S description BINDING SITE FOR RESIDUE CL A 501 source : AC1 2) chain A residue 172 type sequence A description BINDING SITE FOR RESIDUE CL A 501 source : AC1 3) chain A residue 252 type sequence A description BINDING SITE FOR RESIDUE CL A 501 source : AC1 4) chain A residue 253 type sequence H description BINDING SITE FOR RESIDUE CL A 501 source : AC1 5) chain A residue 100 type sequence A description BINDING SITE FOR RESIDUE SO4 A 701 source : AC3 6) chain A residue 165 type sequence R description BINDING SITE FOR RESIDUE SO4 A 701 source : AC3 7) chain A residue 372 type sequence P description BINDING SITE FOR RESIDUE SO4 A 701 source : AC3 8) chain A residue 373 type sequence L description BINDING SITE FOR RESIDUE SO4 A 701 source : AC3 9) chain A residue 382 type sequence R description BINDING SITE FOR RESIDUE SO4 A 701 source : AC3 10) chain A residue 294 type sequence R description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 11) chain A residue 307 type sequence R description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 12) chain A residue 317 type sequence N description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 13) chain A residue 352 type sequence K description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 14) chain A residue 367 type sequence M description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 15) chain A residue 372 type sequence P description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 16) chain A residue 374 type sequence I description BINDING SITE FOR RESIDUE SO4 A 702 source : AC4 17) chain A residue 376 type sequence E description BINDING SITE FOR RESIDUE SO4 A 705 source : AC7 18) chain A residue 377 type sequence H description BINDING SITE FOR RESIDUE SO4 A 705 source : AC7 19) chain A residue 379 type sequence E description BINDING SITE FOR RESIDUE SO4 A 705 source : AC7 20) chain A residue 380 type sequence E description BINDING SITE FOR RESIDUE SO4 A 705 source : AC7 21) chain A residue 169 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 706 source : AC8 22) chain A residue 178 type sequence R description BINDING SITE FOR RESIDUE SO4 A 706 source : AC8 23) chain A residue 204 type sequence K description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 24) chain A residue 248 type sequence K description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 25) chain A residue 252 type sequence A description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 26) chain A residue 253 type sequence H description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 27) chain A residue 254 type sequence A description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 28) chain A residue 255 type sequence G description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 29) chain A residue 258 type sequence K description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 30) chain A residue 284 type sequence E description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 31) chain A residue 285 type sequence A description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 32) chain A residue 287 type sequence I description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 33) chain A residue 292 type sequence D description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 34) chain A residue 314 type sequence W description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 35) chain A residue 315 type sequence K description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 36) chain A residue 316 type sequence A description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 37) chain A residue 317 type sequence N description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 38) chain A residue 352 type sequence K description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 39) chain A residue 364 type sequence I description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 40) chain A residue 365 type sequence E description BINDING SITE FOR RESIDUE ANP A 707 source : AC9 41) chain A residue 226 type sequence V description BINDING SITE FOR RESIDUE EDO A 601 source : BC2 42) chain A residue 227 type sequence E description BINDING SITE FOR RESIDUE EDO A 601 source : BC2 43) chain A residue 362 type sequence Y description BINDING SITE FOR RESIDUE EDO A 601 source : BC2 44) chain A residue 259 type sequence I description BINDING SITE FOR RESIDUE EDO A 602 source : BC3 45) chain A residue 260 type sequence K description BINDING SITE FOR RESIDUE EDO A 602 source : BC3 46) chain A residue 261 type sequence V description BINDING SITE FOR RESIDUE EDO A 602 source : BC3 47) chain A residue 262 type sequence E description BINDING SITE FOR RESIDUE EDO A 602 source : BC3 48) chain A residue 266 type sequence D description BINDING SITE FOR RESIDUE EDO A 602 source : BC3 49) chain A residue 165 type sequence R description BINDING SITE FOR RESIDUE EDO A 603 source : BC4 50) chain A residue 167 type sequence H description BINDING SITE FOR RESIDUE EDO A 603 source : BC4 51) chain A residue 370 type sequence S description BINDING SITE FOR RESIDUE EDO A 603 source : BC4 52) chain A residue 372 type sequence P description BINDING SITE FOR RESIDUE EDO A 603 source : BC4 53) chain A residue 266 type sequence D description BINDING SITE FOR RESIDUE EDO A 604 source : BC5 54) chain A residue 269 type sequence D description BINDING SITE FOR RESIDUE EDO A 604 source : BC5 55) chain A residue 213 type sequence K description BINDING SITE FOR RESIDUE EDO B 607 source : BC8 56) chain A residue 215 type sequence F description BINDING SITE FOR RESIDUE EDO A 608 source : BC9 57) chain A residue 225 type sequence L description BINDING SITE FOR RESIDUE EDO A 608 source : BC9 58) chain A residue 227 type sequence E description BINDING SITE FOR RESIDUE EDO A 608 source : BC9 59) chain A residue 362 type sequence Y description BINDING SITE FOR RESIDUE EDO A 608 source : BC9 60) chain A residue 250-260 type prosite sequence GHAHAGMGKIK description SYNAPSIN_2 Synapsins signature 2. GHAHAGMGKIK source prosite : PS00416

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