eF-site ID 2p0a-B PDB Code 2p0a Chain B click to enlarge Title The crystal structure of human synapsin III (SYN3) in complex with AMPPNP Classification NEUROPEPTIDE Compound Synapsin-3 Source Homo sapiens (Human) (SYN3_HUMAN) Sequence B:  RPRILLVIDDAHTDWSKYFHGKKVNGEIEIRVEQAEFSEL NLAAYVTGGCMVDMQRSFKPDFILVRQHAYSMALGEDYRS LVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLG PEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKI KVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIG SNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSC SEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVE EDRQLMADLVVSKMSQLP Description Functional site 1) chain B residue 170 type sequence S description BINDING SITE FOR RESIDUE CL B 501 source : AC2 2) chain B residue 172 type sequence A description BINDING SITE FOR RESIDUE CL B 501 source : AC2 3) chain B residue 173 type sequence L description BINDING SITE FOR RESIDUE CL B 501 source : AC2 4) chain B residue 252 type sequence A description BINDING SITE FOR RESIDUE CL B 501 source : AC2 5) chain B residue 253 type sequence H description BINDING SITE FOR RESIDUE CL B 501 source : AC2 6) chain B residue 165 type sequence R description BINDING SITE FOR RESIDUE SO4 B 703 source : AC5 7) chain B residue 372 type sequence P description BINDING SITE FOR RESIDUE SO4 B 703 source : AC5 8) chain B residue 373 type sequence L description BINDING SITE FOR RESIDUE SO4 B 703 source : AC5 9) chain B residue 382 type sequence R description BINDING SITE FOR RESIDUE SO4 B 703 source : AC5 10) chain B residue 294 type sequence R description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 11) chain B residue 307 type sequence R description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 12) chain B residue 317 type sequence N description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 13) chain B residue 352 type sequence K description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 14) chain B residue 367 type sequence M description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 15) chain B residue 372 type sequence P description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 16) chain B residue 374 type sequence I description BINDING SITE FOR RESIDUE SO4 B 704 source : AC6 17) chain B residue 178 type sequence R description BINDING SITE FOR RESIDUE SO4 A 706 source : AC8 18) chain B residue 204 type sequence K description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 19) chain B residue 248 type sequence K description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 20) chain B residue 252 type sequence A description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 21) chain B residue 253 type sequence H description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 22) chain B residue 254 type sequence A description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 23) chain B residue 255 type sequence G description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 24) chain B residue 258 type sequence K description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 25) chain B residue 284 type sequence E description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 26) chain B residue 285 type sequence A description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 27) chain B residue 287 type sequence I description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 28) chain B residue 292 type sequence D description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 29) chain B residue 314 type sequence W description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 30) chain B residue 315 type sequence K description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 31) chain B residue 316 type sequence A description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 32) chain B residue 317 type sequence N description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 33) chain B residue 352 type sequence K description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 34) chain B residue 364 type sequence I description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 35) chain B residue 365 type sequence E description BINDING SITE FOR RESIDUE ANP B 705 source : BC1 36) chain B residue 260 type sequence K description BINDING SITE FOR RESIDUE EDO A 604 source : BC5 37) chain B residue 314 type sequence W description BINDING SITE FOR RESIDUE EDO A 604 source : BC5 38) chain B residue 215 type sequence F description BINDING SITE FOR RESIDUE EDO B 605 source : BC6 39) chain B residue 225 type sequence L description BINDING SITE FOR RESIDUE EDO B 605 source : BC6 40) chain B residue 362 type sequence Y description BINDING SITE FOR RESIDUE EDO B 605 source : BC6 41) chain B residue 226 type sequence V description BINDING SITE FOR RESIDUE EDO B 606 source : BC7 42) chain B residue 227 type sequence E description BINDING SITE FOR RESIDUE EDO B 606 source : BC7 43) chain B residue 362 type sequence Y description BINDING SITE FOR RESIDUE EDO B 606 source : BC7 44) chain B residue 185 type sequence Q description BINDING SITE FOR RESIDUE EDO B 607 source : BC8 45) chain B residue 196 type sequence Y description BINDING SITE FOR RESIDUE EDO B 607 source : BC8

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