eF-site ID 2oy0-AB PDB Code 2oy0 Chain A, B click to enlarge Title Crystal structure of the West Nile virus methyltransferase Classification VIRAL PROTEIN Compound Methyltransferase Source West Nile virus (WNV) (Q9Q6P4_WNV) Sequence A:  RTLGEVWKERLNQMTKEEFTRYRKEAIIEVDRSAAKHARK EGNVTGGHPVSRGTAKLRWLVERRFLEPVGKVIDLGCGRG GWCYYMATQKRVQEVRGYTKGGPGHEEPQLVQSYGWNIVT MKSGVDVFYRPSECCDTLLCDIGESSSSAEVEEHRTIRVL EMVEDWLHRGPREFCVKVLCPYMPKVIEKMELLQRRYGGG LVRNPLSRNSTHEMYWVSRASGNVVHSVNMTSQVLLGRME KRTWKGPQYEEDVNLGSGTRAV B:  RTLGEVWKERLNQMTKEEFTRYRKEAIIEVDRSAAKHARK EGNVTGGHPVSRGTAKLRWLVERRFLEPVGKVIDLGCGRG GWCYYMATQKRVQEVRGYTKGGPGHEEPQLVQSYGWNIVT MKSGVDVFYRPSECCDTLLCDIGESSSSAEVEEHRTIRVL EMVEDWLHRGPREFCVKVLCPYMPKVIEKMELLQRRYGGG LVRNPLSRNSTHEMYWVSRASGNVVHSVNMTSQVLLGRME KRTWKGPQYEEDVNLGSGTRAV Description Functional site 1) chain A residue 56 type sequence S description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 2) chain A residue 58 type sequence G description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 3) chain A residue 81 type sequence G description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 4) chain A residue 82 type sequence C description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 5) chain A residue 83 type sequence G description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 6) chain A residue 84 type sequence R description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 7) chain A residue 85 type sequence G description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 8) chain A residue 86 type sequence G description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 9) chain A residue 87 type sequence W description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 10) chain A residue 104 type sequence T description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 11) chain A residue 105 type sequence K description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 12) chain A residue 110 type sequence H description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 13) chain A residue 111 type sequence E description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 14) chain A residue 131 type sequence D description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 15) chain A residue 132 type sequence V description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 16) chain A residue 133 type sequence F description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 17) chain A residue 146 type sequence D description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 18) chain A residue 149 type sequence E description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 19) chain B residue 200 type sequence R description BINDING SITE FOR RESIDUE SAH A 301 source : AC1 20) chain B residue 56 type sequence S description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 21) chain B residue 58 type sequence G description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 22) chain B residue 81 type sequence G description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 23) chain B residue 82 type sequence C description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 24) chain B residue 83 type sequence G description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 25) chain B residue 86 type sequence G description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 26) chain B residue 87 type sequence W description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 27) chain B residue 104 type sequence T description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 28) chain B residue 105 type sequence K description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 29) chain B residue 110 type sequence H description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 30) chain B residue 111 type sequence E description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 31) chain B residue 131 type sequence D description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 32) chain B residue 132 type sequence V description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 33) chain B residue 133 type sequence F description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 34) chain B residue 146 type sequence D description BINDING SITE FOR RESIDUE SAH B 302 source : AC2 35) chain B residue 147 type sequence I description BINDING SITE FOR RESIDUE SAH B 302 source : AC2

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