|
|
eF-site ID
|
2oud-A |
|
PDB Code
|
2oud |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
Crystal structure of the catalytic domain of human MKP5 |
|
Classification
|
HYDROLASE |
|
Compound
|
Dual specificity protein phosphatase 10 |
|
Source
|
Homo sapiens (Human) (DUS10_HUMAN) |
|
|
Sequence
|
A: |
PDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINV
TTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFI
EEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDA
YKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPK
LMGVETVVKEAAALEHH
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
406-416 |
| type |
prosite |
| sequence |
IHCQAGVSRSA
|
| description |
TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCqaGvsRSA
|
| source |
prosite : PS00383
|
|
|
2)
|
chain |
A |
| residue |
408 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000305|PubMed:16806267, ECO:0000305|PubMed:17400920
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|