eF-site ID 2ou2-A PDB Code 2ou2 Chain A click to enlarge Title Acetyltransferase domain of Human HIV-1 Tat interacting protein, 60kDa, isoform 3 Classification TRANSFERASE Compound Histone acetyltransferase HTATIP Source Homo sapiens (Human) (TIP60_HUMAN) Sequence A:  KNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKY GRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKN KSYSQNLCLLAKCFLDHXTLYYDTDPFLFYVMTEYDCKGF HIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFS YELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILQIT INEISEITSIKKEDVISTLQYLNLINYYKGQYILLRIDSK CLHFTP Description Functional site 1) chain A residue 211 type sequence C description BINDING SITE FOR RESIDUE ZN A 490 source : AC1 2) chain A residue 214 type sequence C description BINDING SITE FOR RESIDUE ZN A 490 source : AC1 3) chain A residue 227 type sequence H description BINDING SITE FOR RESIDUE ZN A 490 source : AC1 4) chain A residue 231 type sequence C description BINDING SITE FOR RESIDUE ZN A 490 source : AC1 5) chain A residue 187 type sequence R description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 6) chain A residue 188 type sequence H description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 7) chain A residue 189 type sequence R description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 8) chain A residue 193 type sequence W description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 9) chain A residue 271 type sequence F description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 10) chain A residue 272 type sequence L description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 11) chain A residue 316 type sequence A description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 12) chain A residue 317 type sequence C description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 13) chain A residue 318 type sequence I description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 14) chain A residue 319 type sequence L description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 15) chain A residue 320 type sequence T description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 16) chain A residue 325 type sequence Q description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 17) chain A residue 326 type sequence R description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 18) chain A residue 327 type sequence R description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 19) chain A residue 328 type sequence G description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 20) chain A residue 330 type sequence G description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 21) chain A residue 331 type sequence K description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 22) chain A residue 351 type sequence E description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 23) chain A residue 355 type sequence S description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 24) chain A residue 357 type sequence L description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 25) chain A residue 361 type sequence S description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 26) chain A residue 364 type sequence S description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 27) chain A residue 368 type sequence Q description BINDING SITE FOR RESIDUE ACO A 500 source : AC2 28) chain A residue 351 type ACT_SITE sequence E description Proton donor/acceptor => ECO:0000250|UniProtKB:Q9H7Z6 source Swiss-Prot : SWS_FT_FI2 29) chain A residue 399 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000269|PubMed:17704809 source Swiss-Prot : SWS_FT_FI7 30) chain A residue 364 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:Q9H7Z6 source Swiss-Prot : SWS_FT_FI4 31) chain A residue 208-233 type ZN_FING sequence LYLCEFCLKYGRSLKCLQRHLTKCDL description C2HC MYST-type => ECO:0000255|PROSITE-ProRule:PRU01063, ECO:0000305|Ref.69 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 318 type BINDING sequence I description BINDING => ECO:0000269|Ref.69 source Swiss-Prot : SWS_FT_FI3 33) chain A residue 325 type BINDING sequence Q description BINDING => ECO:0000269|Ref.69 source Swiss-Prot : SWS_FT_FI3 34) chain A residue 355 type BINDING sequence S description BINDING => ECO:0000269|Ref.69 source Swiss-Prot : SWS_FT_FI3 35) chain A residue 275 type MOD_RES sequence X description N6-acetyllysine; by autocatalysis => ECO:0000269|PubMed:24835996, ECO:0000269|Ref.69 source Swiss-Prot : SWS_FT_FI5

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