eF-site ID 2omg-ABCDEF PDB Code 2omg Chain A, B, C, D, E, F click to enlarge Title Structure of human insulin cocrystallized with protamine and urea Classification HORMONE Compound Insulin A chain Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  GIVEQCCTSICSLYQLENYCN B:  FVNQHLCGSHLVEALYLVCGERGFFYTP C:  GIVEQCCTSICSLYQLENYCN D:  FVNQHLCGSHLVEALYLVCGERGFFYTP E:  GIVEQCCTSICSLYQLENYCN F:  FVNQHLCGSHLVEALYLVCGERGFFYTP Description Functional site 1) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC1 2) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC1 3) chain F residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC1 4) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 301 source : AC2 5) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 301 source : AC2 6) chain F residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 301 source : AC2 7) chain A residue 18 type sequence N description BINDING SITE FOR RESIDUE NA A 401 source : AC3 8) chain A residue 20 type sequence C description BINDING SITE FOR RESIDUE NA A 401 source : AC3 9) chain C residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS C 501 source : AC4 10) chain C residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS C 501 source : AC4 11) chain C residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS C 501 source : AC4 12) chain D residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS C 501 source : AC4 13) chain F residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS C 501 source : AC4 14) chain F residue 17 type sequence L description BINDING SITE FOR RESIDUE CRS C 501 source : AC4 15) chain A residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS A 502 source : AC5 16) chain A residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS A 502 source : AC5 17) chain A residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS A 502 source : AC5 18) chain B residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS A 502 source : AC5 19) chain D residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS A 502 source : AC5 20) chain B residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS E 503 source : AC6 21) chain E residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS E 503 source : AC6 22) chain E residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS E 503 source : AC6 23) chain E residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS E 503 source : AC6 24) chain F residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS E 503 source : AC6 25) chain F residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS E 503 source : AC6 26) chain B residue 1 type sequence F description BINDING SITE FOR RESIDUE URE E 601 source : AC7 27) chain E residue 5 type sequence Q description BINDING SITE FOR RESIDUE URE E 601 source : AC7 28) chain E residue 9 type sequence S description BINDING SITE FOR RESIDUE URE E 601 source : AC7 29) chain E residue 10 type sequence I description BINDING SITE FOR RESIDUE URE E 601 source : AC7 30) chain E residue 11 type sequence C description BINDING SITE FOR RESIDUE URE E 601 source : AC7 31) chain E residue 15 type sequence Q description BINDING SITE FOR RESIDUE URE E 601 source : AC7 32) chain A residue 5 type sequence Q description BINDING SITE FOR RESIDUE URE A 602 source : AC8 33) chain A residue 9 type sequence S description BINDING SITE FOR RESIDUE URE A 602 source : AC8 34) chain A residue 10 type sequence I description BINDING SITE FOR RESIDUE URE A 602 source : AC8 35) chain A residue 11 type sequence C description BINDING SITE FOR RESIDUE URE A 602 source : AC8 36) chain C residue 5 type sequence Q description BINDING SITE FOR RESIDUE URE C 603 source : AC9 37) chain C residue 9 type sequence S description BINDING SITE FOR RESIDUE URE C 603 source : AC9 38) chain C residue 10 type sequence I description BINDING SITE FOR RESIDUE URE C 603 source : AC9 39) chain C residue 11 type sequence C description BINDING SITE FOR RESIDUE URE C 603 source : AC9 40) chain C residue 15 type sequence Q description BINDING SITE FOR RESIDUE URE C 603 source : AC9 41) chain A residue 14 type sequence Y description BINDING SITE FOR RESIDUE URE B 604 source : BC1 42) chain B residue 3 type sequence N description BINDING SITE FOR RESIDUE URE B 604 source : BC1 43) chain B residue 6 type sequence L description BINDING SITE FOR RESIDUE URE B 604 source : BC1 44) chain F residue 3 type sequence N description BINDING SITE FOR RESIDUE URE B 604 source : BC1 45) chain F residue 7 type sequence C description BINDING SITE FOR RESIDUE URE B 604 source : BC1 46) chain A residue 7 type sequence C description BINDING SITE FOR RESIDUE URE A 605 source : BC2 47) chain B residue 3 type sequence N description BINDING SITE FOR RESIDUE URE A 605 source : BC2 48) chain D residue 2 type sequence V description BINDING SITE FOR RESIDUE URE A 605 source : BC2 49) chain D residue 3 type sequence N description BINDING SITE FOR RESIDUE URE A 605 source : BC2 50) chain D residue 6 type sequence L description BINDING SITE FOR RESIDUE URE A 605 source : BC2 51) chain C residue 7 type sequence C description BINDING SITE FOR RESIDUE URE D 606 source : BC3 52) chain D residue 3 type sequence N description BINDING SITE FOR RESIDUE URE D 606 source : BC3 53) chain F residue 6 type sequence L description BINDING SITE FOR RESIDUE URE D 606 source : BC3 54) chain A residue 21 type sequence N description BINDING SITE FOR RESIDUE ARF D 701 source : BC4 55) chain D residue 1 type sequence F description BINDING SITE FOR RESIDUE ARF D 701 source : BC4 56) chain D residue 2 type sequence V description BINDING SITE FOR RESIDUE ARF D 701 source : BC4 57) chain D residue 3 type sequence N description BINDING SITE FOR RESIDUE ARF D 701 source : BC4 58) chain D residue 4 type sequence Q description BINDING SITE FOR RESIDUE ARF D 701 source : BC4 59) chain C residue 9 type sequence S description BINDING SITE FOR RESIDUE ARF F 702 source : BC5 60) chain C residue 10 type sequence I description BINDING SITE FOR RESIDUE ARF F 702 source : BC5 61) chain F residue 1 type sequence F description BINDING SITE FOR RESIDUE ARF F 702 source : BC5 62) chain B residue 1 type sequence F description BINDING SITE FOR RESIDUE ARF B 703 source : BC6 63) chain E residue 9 type sequence S description BINDING SITE FOR RESIDUE ARF B 703 source : BC6 64) chain E residue 10 type sequence I description BINDING SITE FOR RESIDUE ARF B 703 source : BC6 65) chain A residue 1 type sequence G description BINDING SITE FOR RESIDUE ARF A 704 source : BC7 66) chain A residue 5 type sequence Q description BINDING SITE FOR RESIDUE ARF A 704 source : BC7 67) chain E residue 1 type sequence G description BINDING SITE FOR RESIDUE ARF E 705 source : BC8 68) chain A residue 6-20 type prosite sequence CCTSICSLYQLENYC description INSULIN Insulin family signature. CCTSiCSlyqLenyC source prosite : PS00262

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